Gene Symbol | CAPN8 |
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Entrez Gene | 388743 |
Alt Symbol | nCL-2 |
Species | Human |
Gene Type | protein-coding |
Description | calpain 8 |
Other Description | calpain-8|new calpain 2|stomach-specific M-type calpain |
Swissprots | A6NHC0 B2RXL2 |
Accessions | A6NHC0 BC157893 AAI57894 BG187068 BM739137 BM843240 DA874912 NM_001143962 NP_001137434 |
Function | Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. |
Tissue Specificity | Stomach. |
Calpain 8 CRISPR/Cas9 KO Plasmid (h) - sc-402847 from Santa Cruz Biotechnology
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Calpain 8 HDR Plasmid (h) - sc-402847-HDR from Santa Cruz Biotechnology
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Calpain 8 Double Nickase Plasmid (h) - sc-402847-NIC from Santa Cruz Biotechnology
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Calpain 8 Double Nickase Plasmid (h2) - sc-402847-NIC-2 from Santa Cruz Biotechnology
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Calpain 8 CRISPR Activation Plasmid (h) - sc-402847-ACT from Santa Cruz Biotechnology
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Calpain 8 CRISPR Activation Plasmid (h2) - sc-402847-ACT-2 from Santa Cruz Biotechnology
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Calpain 8 Lentiviral Activation Particles (h) - sc-402847-LAC from Santa Cruz Biotechnology
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Calpain 8 Lentiviral Activation Particles (h2) - sc-402847-LAC-2 from Santa Cruz Biotechnology
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Calpain 8 siRNA (h) - sc-78999 from Santa Cruz Biotechnology
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Calpain 8 shRNA Plasmid (h) - sc-78999-SH from Santa Cruz Biotechnology
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Calpain 8 shRNA (h) Lentiviral Particles - sc-78999-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5348 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5348 from Sigma-Aldrich
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CAPN8 siRNA (Human) - CRJ7836 from Cohesion Biosciences
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CAPN8 - MBS8237061 from MyBioSource
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shRNA set against Human Capn8 (NM_001143962.1) - SHH254393 from Creative biogene
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Human CAPN8 siRNA - orb278337 from Biorbyt
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CAPN8 shRNA Plasmid (Human) - CHJ7836 from Cohesion Biosciences
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CAPN8 miRNA 3'UTR clone - MiUTR3H-14284 from Creative biogene
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