| Gene Symbol | ITGA11 |
|---|---|
| Entrez Gene | 22801 |
| Alt Symbol | HsT18964 |
| Species | Human |
| Gene Type | protein-coding |
| Description | integrin, alpha 11 |
| Other Description | integrin alpha-11 |
| Swissprots | J3KQM2 Q8WYI8 Q9UKQ1 Q9UKX5 |
| Accessions | EAW77820 EAW77821 Q9UKX5 AF109681 AAF01258 AF111799 AAL39001 AF137378 AAD51919 AK095863 BAG53148 AK292445 BAF85134 AK304778 BAG65532 AL117454 AL359064 CAB94392 BC167840 AAI67840 BX496541 CN358985 Z50157 Z50167 XM_005254228 XP_005254285 XM_011521363 XP_011519665 NM_001004439 NP_001004439 NM_012211 |
| Function | Integrin alpha-11/beta-1 is a receptor for collagen. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver. {ECO:0000269|PubMed:10464311}. |
| Top Pathways | Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
Panoply™ Human ITGA11 Knockdown Stable Cell Line - CSC-DC007785 from Creative biogene
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