Gene Symbol | ITGA11 |
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Entrez Gene | 22801 |
Alt Symbol | HsT18964 |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha 11 |
Other Description | integrin alpha-11 |
Swissprots | J3KQM2 Q8WYI8 Q9UKQ1 Q9UKX5 |
Accessions | EAW77820 EAW77821 Q9UKX5 AF109681 AAF01258 AF111799 AAL39001 AF137378 AAD51919 AK095863 BAG53148 AK292445 BAF85134 AK304778 BAG65532 AL117454 AL359064 CAB94392 BC167840 AAI67840 BX496541 CN358985 Z50157 Z50167 XM_005254228 XP_005254285 XM_011521363 XP_011519665 NM_001004439 NP_001004439 NM_012211 |
Function | Integrin alpha-11/beta-1 is a receptor for collagen. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver. {ECO:0000269|PubMed:10464311}. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
Integrin α11 CRISPR/Cas9 KO Plasmid (h) - sc-402541 from Santa Cruz Biotechnology
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Integrin α11 HDR Plasmid (h) - sc-402541-HDR from Santa Cruz Biotechnology
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Integrin α11 Double Nickase Plasmid (h) - sc-402541-NIC from Santa Cruz Biotechnology
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Integrin α11 Double Nickase Plasmid (h2) - sc-402541-NIC-2 from Santa Cruz Biotechnology
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Integrin α11 CRISPR Activation Plasmid (h) - sc-402541-ACT from Santa Cruz Biotechnology
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Integrin α11 CRISPR Activation Plasmid (h2) - sc-402541-ACT-2 from Santa Cruz Biotechnology
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Integrin α11 Lentiviral Activation Particles (h) - sc-402541-LAC from Santa Cruz Biotechnology
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Integrin α11 Lentiviral Activation Particles (h2) - sc-402541-LAC-2 from Santa Cruz Biotechnology
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Integrin α11 siRNA (h) - sc-90047 from Santa Cruz Biotechnology
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Integrin α11 shRNA Plasmid (h) - sc-90047-SH from Santa Cruz Biotechnology
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Integrin α11 shRNA (h) Lentiviral Particles - sc-90047-V from Santa Cruz Biotechnology
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Integrin alpha 11 RNAi - H00022801-R01 from Novus Biologicals
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MISSION® esiRNA - EHU145321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10807 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10807 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08938 from Sigma-Aldrich
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ITGA11 siRNA (Human) - CRH7780 from Cohesion Biosciences
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Integrin alpha 11 RNAi - H00022801-R02 from Novus Biologicals
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ITGA11 - MBS8230027 from MyBioSource
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shRNA set against Human Itga11 (NM_001004439.1) - SHH321149 from Creative biogene
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Human ITGA11 siRNA - orb268282 from Biorbyt
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ITGA11 shRNA Plasmid (Human) - CHH7780 from Cohesion Biosciences
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ITGA11 miRNA 3'UTR clone - MiUTR1H-05018 from Creative biogene
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