Gene Symbol |
HES2
|
Entrez Gene |
54626
|
Alt Symbol |
bHLHb40
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
hes family bHLH transcription factor 2
|
Other Description |
class B basic helix-loop-helix protein 40|hairy and enhancer of split 2|transcription factor HES-2
|
Swissprots |
Q96EN4 A2RTZ9 Q9Y543 Q9Y542
|
Accessions |
EAW71533 EAW71534 Q9Y543 AK023754 AK091122 BAG52286 BC012091 AAH12091 BC132698 AAI32699 BC136963 AAI36964 BC142687 AAI42688 BU729177 XM_011541612 XP_011539914 XM_011541613 XP_011539915 NM_019089 NP_061962
|
Function |
Transcriptional repressor of genes that require a bHLH protein for their transcription. {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
|
Tissue Specificity |
Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors. {ECO:0000269|PubMed:15254753}.
|