Gene Symbol | HES2 |
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Entrez Gene | 54626 |
Alt Symbol | bHLHb40 |
Species | Human |
Gene Type | protein-coding |
Description | hes family bHLH transcription factor 2 |
Other Description | class B basic helix-loop-helix protein 40|hairy and enhancer of split 2|transcription factor HES-2 |
Swissprots | Q96EN4 A2RTZ9 Q9Y543 Q9Y542 |
Accessions | EAW71533 EAW71534 Q9Y543 AK023754 AK091122 BAG52286 BC012091 AAH12091 BC132698 AAI32699 BC136963 AAI36964 BC142687 AAI42688 BU729177 XM_011541612 XP_011539914 XM_011541613 XP_011539915 NM_019089 NP_061962 |
Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. |
Tissue Specificity | Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors. {ECO:0000269|PubMed:15254753}. |
HES2 CRISPR/Cas9 KO Plasmid (h) - sc-407494 from Santa Cruz Biotechnology
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HES2 HDR Plasmid (h) - sc-407494-HDR from Santa Cruz Biotechnology
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HES2 Double Nickase Plasmid (h) - sc-407494-NIC from Santa Cruz Biotechnology
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HES2 Double Nickase Plasmid (h2) - sc-407494-NIC-2 from Santa Cruz Biotechnology
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HES2 CRISPR Activation Plasmid (h) - sc-407494-ACT from Santa Cruz Biotechnology
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HES2 CRISPR Activation Plasmid (h2) - sc-407494-ACT-2 from Santa Cruz Biotechnology
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HES2 Lentiviral Activation Particles (h) - sc-407494-LAC from Santa Cruz Biotechnology
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HES2 Lentiviral Activation Particles (h2) - sc-407494-LAC-2 from Santa Cruz Biotechnology
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HES2 siRNA (h) - sc-37940 from Santa Cruz Biotechnology
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HES2 shRNA Plasmid (h) - sc-37940-SH from Santa Cruz Biotechnology
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HES2 shRNA (h) Lentiviral Particles - sc-37940-V from Santa Cruz Biotechnology
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HES2 RNAi - H00054626-R01 from Novus Biologicals
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MISSION® esiRNA - EHU097891 from Sigma-Aldrich
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MISSION® esiRNA - EHU141241 from Sigma-Aldrich
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MISSION® esiRNA - EHU093331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9993 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9993 from Sigma-Aldrich
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HES2 siRNA (Human) - CRJ0161 from Cohesion Biosciences
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HES2 - MBS826999 from MyBioSource
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shRNA set against Human HES2 (NM_019089.4) - SHH311689 from Creative biogene
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HES2 CRISPR/Cas9 KO Plasmid (h2) - sc-407494-KO-2 from Santa Cruz Biotechnology
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HES2 HDR Plasmid (h2) - sc-407494-HDR-2 from Santa Cruz Biotechnology
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HES2 shRNA Plasmid (Human) - CHJ0161 from Cohesion Biosciences
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HES2 miRNA 3'UTR clone - MiUTR4H-TG04152 from Creative biogene
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