Gene Symbol | SEMA6A |
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Entrez Gene | 57556 |
Alt Symbol | HT018, SEMA, SEMA6A1, SEMAQ, VIA |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
Other Description | SEMA6A-1|sema VIa|semaphorin 6A-1|semaphorin VIA|semaphorin-6A|semaphorin-6A-1 |
Swissprots | Q9P2H9 Q9H2E6 |
Accessions | EAW48934 EAW48935 EAW48936 EAW48937 EAW48938 Q9H2E6 AB037789 BAA92606 AF225425 AAG09727 AF279656 AAG29378 AI110626 AK027439 BAB55111 AK027471 BAB55136 AK027501 BAB55158 AK027505 AK027654 BAB55269 AK027867 BAB55418 AK074975 BAC11326 AK096337 BAG53263 AK302928 BAH13847 AK315143 BAG37591 AL544905 BC032619 BC156173 AAI56174 BC172468 AAI72468 CX164544 XM_005272042 XP_005272099 XM_006714663 XP_006714726 NM_020681 NM_001300780 NP_001287709 NM_020796 NP_065847 |
Function | Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Axon guidance |
SEMA6A (B-3) - sc-398302 from Santa Cruz Biotechnology
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SEMA6A (H-180) - sc-292660 from Santa Cruz Biotechnology
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SEMA6A (K-19) - sc-67962 from Santa Cruz Biotechnology
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SEMA6A (S-18) - sc-67964 from Santa Cruz Biotechnology
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Anti-Sema6A antibody - ab34818 from Abcam
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Anti-Sema6A antibody [MM0534-8D9] - ab90239 from Abcam
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Anti-Sema6A antibody - C-terminal - ab72369 from Abcam
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Anti-Sema6A antibody - N-terminal - ab174520 from Abcam
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Anti-SEMA6A / Semaphorin 6A Antibody (aa998-1028) - LS-C98615 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa19-649, APC) - LS-C126265 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody - LS-C126263 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57, APC) - LS-C268965 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57, AP) - LS-C268966 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57, Azide-free, HRP) - LS-C268969 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57, FITC) - LS-C268968 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57, PE) - LS-C268970 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57, Biotin) - LS-C268967 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa36-65) - LS-C324994 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa359-408) - LS-C107651 from LifeSpan Bioscience
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Anti-SEMA6A / Semaphorin 6A Antibody (aa29-57) - LS-C168957 from LifeSpan Bioscience
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Semaphorin 6A Antibody - NBP1-31551 from Novus Biologicals
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Semaphorin 6A Antibody - AF1146 from Novus Biologicals
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Semaphorin 6A Antibody - AF1615 from Novus Biologicals
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Semaphorin 6A Antibody - NBP1-69281 from Novus Biologicals
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Semaphorin 6A Antibody (104B3) - DDX0462P-100 from Novus Biologicals
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