Gene Symbol |
SLC1A6
|
Entrez Gene |
6511
|
Alt Symbol |
EAAT4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
|
Other Description |
excitatory amino acid transporter 4|sodium-dependent glutamate/aspartate transporter|solute carrier family 1 member 6
|
Swissprots |
Q8N753 P48664
|
Accessions |
AAC15754 EAW84456 EAW84457 P48664 AB209199 BAD92436 AK302380 BAH13691 AK312996 BC028721 AAH28721 BC040604 AAH40604 BI829415 DA059558 DA200776 DB027852 DR004792 HY352099 U18244 AAA75314 XM_006722842 XP_006722905 XM_006722843 XP_006722906 XM_006722844 XP_006722907 NM_001272087 NP_001259016 NM_001272088 NP_001259017 NM_005071 NP_005062 NR_073589
|
Function |
Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Brain. Expressed densely and selectively in cell bodies of Purkinje cells.
|
Top Pathways |
Glutamatergic synapse
|