Gene Symbol | SLC1A6 |
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Entrez Gene | 6511 |
Alt Symbol | EAAT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
Other Description | excitatory amino acid transporter 4|sodium-dependent glutamate/aspartate transporter|solute carrier family 1 member 6 |
Swissprots | Q8N753 P48664 |
Accessions | AAC15754 EAW84456 EAW84457 P48664 AB209199 BAD92436 AK302380 BAH13691 AK312996 BC028721 AAH28721 BC040604 AAH40604 BI829415 DA059558 DA200776 DB027852 DR004792 HY352099 U18244 AAA75314 XM_006722842 XP_006722905 XM_006722843 XP_006722906 XM_006722844 XP_006722907 NM_001272087 NP_001259016 NM_001272088 NP_001259017 NM_005071 NP_005062 NR_073589 |
Function | Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Brain. Expressed densely and selectively in cell bodies of Purkinje cells. |
Top Pathways | Glutamatergic synapse |
EAAT4 CRISPR/Cas9 KO Plasmid (h) - sc-404277 from Santa Cruz Biotechnology
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EAAT4 HDR Plasmid (h) - sc-404277-HDR from Santa Cruz Biotechnology
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EAAT4 Double Nickase Plasmid (h) - sc-404277-NIC from Santa Cruz Biotechnology
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EAAT4 Double Nickase Plasmid (h2) - sc-404277-NIC-2 from Santa Cruz Biotechnology
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EAAT4 CRISPR Activation Plasmid (h) - sc-404277-ACT from Santa Cruz Biotechnology
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EAAT4 CRISPR Activation Plasmid (h2) - sc-404277-ACT-2 from Santa Cruz Biotechnology
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EAAT4 Lentiviral Activation Particles (h) - sc-404277-LAC from Santa Cruz Biotechnology
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EAAT4 Lentiviral Activation Particles (h2) - sc-404277-LAC-2 from Santa Cruz Biotechnology
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EAAT4 siRNA (h) - sc-41942 from Santa Cruz Biotechnology
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EAAT4 shRNA Plasmid (h) - sc-41942-SH from Santa Cruz Biotechnology
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EAAT4 shRNA (h) Lentiviral Particles - sc-41942-V from Santa Cruz Biotechnology
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EAAT4 RNAi - H00006511-R01 from Novus Biologicals
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MISSION® esiRNA - EHU061991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19450 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19450 from Sigma-Aldrich
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SLC1A6 siRNA (Human) - CRH4406 from Cohesion Biosciences
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SLC1A6 - MBS8232219 from MyBioSource
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shRNA set against Human SLC1A6 (NM_005071.1) - SHH408956 from Creative biogene
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shRNA set against Human SLC1A6(NM_005071.1) - SHL000696 from Creative biogene
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Human SLC1A6 siRNA - orb264908 from Biorbyt
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SLC1A6 shRNA Plasmid (Human) - CHH4406 from Cohesion Biosciences
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SLC1A6 miRNA 3'UTR clone - MiUTR1H-09453 from Creative biogene
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