| Gene Symbol |
NETO1
|
| Entrez Gene |
81832
|
| Alt Symbol |
BCTL1, BTCL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropilin (NRP) and tolloid (TLL)-like 1
|
| Other Description |
brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1|neuropilin and tolloid-like protein 1
|
| Swissprots |
Q8TDF4 Q86W85 Q8ND78 Q8TDF5
|
| Accessions |
EAW66530 EAW66531 EAW66532 EAW66533 Q8TDF5 AF448838 AAM18026 AF448839 AAM18027 AK123319 AL834354 CAD39019 BC050329 AAH50329 BU739516 HG510130 XM_005266774 XP_005266831 XM_005266776 XP_005266833 XM_011526218 XP_011524520 XR_935254 XR_935255 XR_935256 XR_935257 NM_001201465 NP_001188394 NM_138966 NP_620416 NM_138999 NP_620552 NM_153181
|
| Function |
Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D- aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Isoform 1: Secreted {ECO:0000305}.
|
| Tissue Specificity |
Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain. {ECO:0000269|PubMed:11943477}.
|
