Gene Symbol | NETO1 |
---|---|
Entrez Gene | 81832 |
Alt Symbol | BCTL1, BTCL1 |
Species | Human |
Gene Type | protein-coding |
Description | neuropilin (NRP) and tolloid (TLL)-like 1 |
Other Description | brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1|neuropilin and tolloid-like protein 1 |
Swissprots | Q8TDF4 Q86W85 Q8ND78 Q8TDF5 |
Accessions | EAW66530 EAW66531 EAW66532 EAW66533 Q8TDF5 AF448838 AAM18026 AF448839 AAM18027 AK123319 AL834354 CAD39019 BC050329 AAH50329 BU739516 HG510130 XM_005266774 XP_005266831 XM_005266776 XP_005266833 XM_011526218 XP_011524520 XR_935254 XR_935255 XR_935256 XR_935257 NM_001201465 NP_001188394 NM_138966 NP_620416 NM_138999 NP_620552 NM_153181 |
Function | Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D- aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform 1: Secreted {ECO:0000305}. |
Tissue Specificity | Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain. {ECO:0000269|PubMed:11943477}. |
NETO1 CRISPR/Cas9 KO Plasmid (h) - sc-417134 from Santa Cruz Biotechnology
|
||||||||
NETO1 HDR Plasmid (h) - sc-417134-HDR from Santa Cruz Biotechnology
|
||||||||
NETO1 Double Nickase Plasmid (h) - sc-417134-NIC from Santa Cruz Biotechnology
|
||||||||
NETO1 Double Nickase Plasmid (h2) - sc-417134-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NETO1 CRISPR Activation Plasmid (h) - sc-417134-ACT from Santa Cruz Biotechnology
|
||||||||
NETO1 CRISPR Activation Plasmid (h2) - sc-417134-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NETO1 Lentiviral Activation Particles (h) - sc-417134-LAC from Santa Cruz Biotechnology
|
||||||||
NETO1 Lentiviral Activation Particles (h2) - sc-417134-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NETO1 siRNA (h) - sc-75901 from Santa Cruz Biotechnology
|
||||||||
NETO1 shRNA Plasmid (h) - sc-75901-SH from Santa Cruz Biotechnology
|
||||||||
NETO1 shRNA (h) Lentiviral Particles - sc-75901-V from Santa Cruz Biotechnology
|
||||||||
NETO1 RNAi - H00081832-R04 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU139961 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15213 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15213 from Sigma-Aldrich
|
||||||||
NETO1 siRNA (Human) - CRJ3057 from Cohesion Biosciences
|
||||||||
NETO1 RNAi - H00081832-R06 from Novus Biologicals
|
||||||||
NETO1 RNAi - H00081832-R05 from Novus Biologicals
|
||||||||
shRNA set against Human NETO1 (NM_138999.1) - SHH351420 from Creative biogene
|
||||||||
Human NETO1 siRNA - orb273558 from Biorbyt
|
||||||||
NETO1 shRNA Plasmid (Human) - CHJ3057 from Cohesion Biosciences
|
||||||||
NETO1 miRNA 3'UTR clone - MiUTR1H-06723 from Creative biogene
|
||||||||
NETO1 miRNA 3'UTR clone - MiUTR3H-09624 from Creative biogene
|