UGT2B11

Gene Symbol UGT2B11
Entrez Gene 10720
Alt Symbol -
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 2 family, polypeptide B11
Other Description UDP glycosyltransferase 2 family protein|UDP glycosyltransferase 2 family, polypeptide B11|UDP-glucuronosyltransferase 2B11|UDPGT 2B11
Swissprots O75310 Q3KNV9
Accessions AAF78146 AAY41046 EAX05586 EAX05587 O75310 AF016492 AAC27891 BC069441 AAH69441 BC107059 AAI07060 BC107060 AAI07061 XM_011531550 XP_011529852 XM_011531551 XP_011529853 NM_001073 NP_001064
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Subcellular Location Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450