Gene Symbol | UGT2B11 |
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Entrez Gene | 10720 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | UDP glucuronosyltransferase 2 family, polypeptide B11 |
Other Description | UDP glycosyltransferase 2 family protein|UDP glycosyltransferase 2 family, polypeptide B11|UDP-glucuronosyltransferase 2B11|UDPGT 2B11 |
Swissprots | O75310 Q3KNV9 |
Accessions | AAF78146 AAY41046 EAX05586 EAX05587 O75310 AF016492 AAC27891 BC069441 AAH69441 BC107059 AAI07060 BC107060 AAI07061 XM_011531550 XP_011529852 XM_011531551 XP_011529853 NM_001073 NP_001064 |
Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. |
Subcellular Location | Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |
UGT2B11 CRISPR/Cas9 KO Plasmid (h) - sc-417156 from Santa Cruz Biotechnology
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UGT2B11 HDR Plasmid (h) - sc-417156-HDR from Santa Cruz Biotechnology
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UGT2B11 Double Nickase Plasmid (h) - sc-417156-NIC from Santa Cruz Biotechnology
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UGT2B11 Double Nickase Plasmid (h2) - sc-417156-NIC-2 from Santa Cruz Biotechnology
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UGT2B11 CRISPR Activation Plasmid (h) - sc-417156-ACT from Santa Cruz Biotechnology
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UGT2B11 CRISPR Activation Plasmid (h2) - sc-417156-ACT-2 from Santa Cruz Biotechnology
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UGT2B11 Lentiviral Activation Particles (h) - sc-417156-LAC from Santa Cruz Biotechnology
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UGT2B11 Lentiviral Activation Particles (h2) - sc-417156-LAC-2 from Santa Cruz Biotechnology
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UGT2B11 siRNA (h) - sc-106668 from Santa Cruz Biotechnology
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UGT2B11 shRNA Plasmid (h) - sc-106668-SH from Santa Cruz Biotechnology
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UGT2B11 shRNA (h) Lentiviral Particles - sc-106668-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22468 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22468 from Sigma-Aldrich
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UGT2B11 siRNA (Human) - CRH7303 from Cohesion Biosciences
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UGT2B11 - MBS8210049 from MyBioSource
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shRNA set against Human UGT2B11(NM_001073.1) - SHL113484 from Creative biogene
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UGT2B11 shRNA Plasmid (Human) - CHH7303 from Cohesion Biosciences
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UGT2B11 miRNA 3'UTR clone - MiUTR1H-10996 from Creative biogene
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