Gene Symbol |
UGT2B11
|
Entrez Gene |
10720
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
UDP glucuronosyltransferase 2 family, polypeptide B11
|
Other Description |
UDP glycosyltransferase 2 family protein|UDP glycosyltransferase 2 family, polypeptide B11|UDP-glucuronosyltransferase 2B11|UDPGT 2B11
|
Swissprots |
O75310 Q3KNV9
|
Accessions |
AAF78146 AAY41046 EAX05586 EAX05587 O75310 AF016492 AAC27891 BC069441 AAH69441 BC107059 AAI07060 BC107060 AAI07061 XM_011531550 XP_011529852 XM_011531551 XP_011529853 NM_001073 NP_001064
|
Function |
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
|
Subcellular Location |
Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
Tissue Specificity |
Widely expressed.
|
Top Pathways |
Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450
|