| Gene Symbol |
Nobox
|
| Entrez Gene |
18291
|
| Alt Symbol |
OG2, Og2x
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
NOBOX oogenesis homeobox
|
| Other Description |
OG2 homeobox|homeobox protein NOBOX|homeodomain-containing protein OG-2|newborn ovary homeobox protein|oocyte-specific homeobox protein
|
| Swissprots |
P70367 Q8VIH1
|
| Accessions |
AAC52828 EDL13447 Q8VIH1 AB221582 AY061761 AAL29683 BC125280 AAI25281 BC125282 AAI25283 XM_006505717 XP_006505780 XM_006505719 XP_006505782 NM_130869 NP_570939
|
| Function |
Transcription factor which plays an essential role in postnatal follicle development. Binds preferentially to the DNA sequences 5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3'. Directly regulates the transcription of POU5F1 and GDF9 during early folliculogenesis. {ECO:0000269|PubMed:15326356, ECO:0000269|PubMed:16997917}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Specifically expressed in ovaries and testes. In ovaries, expressed in oocytes from primordial through antral follicles but not in granulosa cells, theca cells and corpora lutea. {ECO:0000269|PubMed:11804785}.
|