Gene Symbol | P2RY2 |
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Entrez Gene | 5029 |
Alt Symbol | HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2Y, G-protein coupled, 2 |
Other Description | ATP receptor|P2U nucleotide receptor|P2U purinoceptor 1|P2U receptor 1|P2Y purinoceptor 2|purinergic receptor P2Y2|purinoceptor P2Y2 |
Swissprots | B2R9W3 Q96EM8 P41231 |
Accessions | EAW74882 EAW74883 EAW74884 P41231 AK094727 AK313942 BAG36660 AY136753 AAN01279 BC012104 AAH12104 BC028135 AAH28135 BX641058 DQ892258 ABM83184 DQ895460 ABM86386 FJ599699 ACS66693 FJ599700 ACS66694 HG503966 U07225 AAC04923 XM_005274019 XP_005274076 XM_005274020 XP_005274077 XM_005274021 XP_005274078 XM_011545074 XP_011543376 NM_002564 NP_002555 NM_176071 NP_788085 NM_176072 NP_788086 |
Function | Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Spleen, testis, kidney, liver, lung, heart and brain. |
Top Pathways | Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction |
Human P2Y2 full length protein - ab132032 from Abcam
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P2Y2 peptide - ab111724 from Abcam
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P2RY2 / P2Y2 Antibody Blocking Peptide - LS-E3542 from LifeSpan Bioscience
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P2RY2 / P2Y2 Antibody Blocking Peptide - LS-E23071 from LifeSpan Bioscience
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P2RY2 / P2Y2 Antibody Blocking Peptide - LS-E23072 from LifeSpan Bioscience
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Recombinant Human P2Y2 Protein - H00005029-P01 from Novus Biologicals
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P2RY2-Antibody-C-term-Blocking-Peptide - BP14740b from Abgent, a WuXi AppTec company
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P2RY2 / P2Y2 - H00005029-G01 from Acris Antibodies
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P2RY2 / P2Y2 - H00005029-P01-10 from Acris Antibodies
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P2RY2 / P2Y2 - H00005029-P01-25 from Acris Antibodies
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P2Y2 Peptide - 214-10018 from RayBiotech
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P2RY2 fusion protein - ag14107 from Proteintech Group
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P2RY2 fusion protein - Ag14499 from Proteintech Group
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Recombinant Human P2RY2, GST-tagged - P2RY2-1498H from Creative Biomart
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P2Y2 Recombinant Protein - H00005029-G01 from Novus Biologicals
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P2Y purinoceptor 2 (P2RY2), Recombinant Protein - MBS965930 from MyBioSource
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ChemiSCREEN™ Human Recombinant P2Y2 Purinergic Receptor Calcium-Optimized Stable Cell Line - HTS210C from EMD Millipore
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P2RY2 Peptide, Human - M34GP11210H from Creative Peptides
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P2Y purinoceptor 2 (P2RY2), Recombinant Protein - MBS7025285 from MyBioSource
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P2Y2 peptide - orb319741 from Biorbyt
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