CALR

Gene Symbol CALR
Entrez Gene 281036
Alt Symbol -
Species Bovine
Gene Type protein-coding
Description calreticulin
Other Description CRP55|HACBP|calrectulin|calregulin
Swissprots P28489 Q8SQ53 P42918 P52193
Accessions DAA28020 P52193 AB067687 BAB86913 BC140582 AAI40583 L13462 AAC37307 NM_174000 NP_776425
Function Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:12782144}. Sarcoplasmic reticulum lumen {ECO:0000250}.
Top Pathways Chagas disease (American trypanosomiasis), Phagosome, Protein processing in endoplasmic reticulum, HTLV-I infection, Antigen processing and presentation

Anti-Calreticulin [5] antibody - ab191847 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5
Anti-Calreticulin [5] antibody (ab191847) at 1/1000 dilution + HeLa whole cell lysate

Anti-Calreticulin antibody - ab94935 from Abcam

Prices $378.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal
Anti-Calreticulin antibody (ab94935) at 1/1000 dilution + AtT-20 cell lysate

Anti-Calreticulin antibody - ab15607 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot using ab15607 at 1/1000 on mouse embyronic fibroblast lysate.

Anti-Calreticulin antibody - ab188115 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
All lanes : Anti-Calreticulin antibody (ab188115) at 0.01 µg/ml (incubated for 1 hour)Lane 1 : Human lung lysateLane 2 : Rat lung lysateLysates/proteins at 35 µg per lane.developed using the ECL technique

Anti-Calreticulin antibody - ab4 from Abcam

Prices $400.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Calreticulin antibody (ab4) at 1/1000 dilutionLane 1 : Chicken lymphoid cell line lysateLane 2 : Chicken lymphoid cell line lysateLysates/proteins at 1000000 cells per lane.SecondaryPolyclonal HRP-conjugate Goat anti-rabbit IgG at 1/2000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Calreticulin antibody [FMC 75] (Phycoerythrin) - ab83220 from Abcam

Prices $378.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone FMC 75
Intracellular staining of 106 Jurkat cells using ab83220 at a concentration of 10µg/ml.

Anti-Calreticulin antibody - ER Marker - ab128885 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Calreticulin antibody - ER Marker (ab128885) at 1 µg/ml (Milk blocking - 3%)Lane 1 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell LysateLane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.
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