| Gene Symbol |
EFS
|
| Entrez Gene |
10278
|
| Alt Symbol |
CAS3, CASS3, EFS1, EFS2, HEFS, SIN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
embryonal Fyn-associated substrate
|
| Other Description |
Cas scaffolding protein family member 3|signal transduction protein (SH3 containing)
|
| Swissprots |
B4DJ56 B2RAJ7 O43282 E9PGU2 O43281
|
| Accessions |
EAW66163 EAW66164 O43281 AA470981 AB001466 BAA24588 AB001467 BAA24589 AI808817 AK295933 BAG58718 AK314221 BAG36894 BC034246 AAH34246 BC046403 BE645250 XM_005267256 XP_005267313 NM_001277174 NP_001264103 NM_005864 NP_005855 NM_032459 NP_115835
|
| Function |
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
The protein has been detected in lung and placenta.
|