| Gene Symbol | EFS |
|---|---|
| Entrez Gene | 10278 |
| Alt Symbol | CAS3, CASS3, EFS1, EFS2, HEFS, SIN |
| Species | Human |
| Gene Type | protein-coding |
| Description | embryonal Fyn-associated substrate |
| Other Description | Cas scaffolding protein family member 3|signal transduction protein (SH3 containing) |
| Swissprots | B4DJ56 B2RAJ7 O43282 E9PGU2 O43281 |
| Accessions | EAW66163 EAW66164 O43281 AA470981 AB001466 BAA24588 AB001467 BAA24589 AI808817 AK295933 BAG58718 AK314221 BAG36894 BC034246 AAH34246 BC046403 BE645250 XM_005267256 XP_005267313 NM_001277174 NP_001264103 NM_005864 NP_005855 NM_032459 NP_115835 |
| Function | Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity). {ECO:0000250}. |
| Tissue Specificity | The protein has been detected in lung and placenta. |
MISSION® esiRNA - EHU065981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7704 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7704 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07238 from Sigma-Aldrich
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EFS siRNA (Human) - CRH6959 from Cohesion Biosciences
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EFS - MBS8221527 from MyBioSource
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shRNA set against Human EFS (NM_005864.2) - SHH283741 from Creative biogene
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shRNA set against Human EFS(NM_032459.1) - SHH026057 from Creative biogene
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EFS shRNA Plasmid (Human) - CHH6959 from Cohesion Biosciences
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EFS miRNA 3'UTR clone - MiUTR1H-03131 from Creative biogene
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EFS miRNA 3'UTR clone - MiUTR1H-03132 from Creative biogene
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