Gene Symbol |
STX8
|
Entrez Gene |
9482
|
Alt Symbol |
CARB
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
syntaxin 8
|
Other Description |
CIP-1-associated regulator of cyclin B|syntaxin-8
|
Swissprots |
Q53XT8 O60712 Q9UNK0
|
Accessions |
EAW90028 EAW90029 EAW90030 EAW90031 Q9UNK0 AF036715 AAC95285 AF062077 AAC36466 AF115323 AAD20831 BC009713 AAH09713 BC020924 BT007319 AAP35983 BU596252 DQ890985 ABM81911 DQ894161 ABM85087 XM_011524079 XP_011522381 XR_934120 NM_004853 NP_004844 NR_033656
|
Function |
Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.
|
Subcellular Location |
Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits (By similarity). {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.
|
Top Pathways |
SNARE interactions in vesicular transport
|