Gene Symbol | STX8 |
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Entrez Gene | 9482 |
Alt Symbol | CARB |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin 8 |
Other Description | CIP-1-associated regulator of cyclin B|syntaxin-8 |
Swissprots | Q53XT8 O60712 Q9UNK0 |
Accessions | EAW90028 EAW90029 EAW90030 EAW90031 Q9UNK0 AF036715 AAC95285 AF062077 AAC36466 AF115323 AAD20831 BC009713 AAH09713 BC020924 BT007319 AAP35983 BU596252 DQ890985 ABM81911 DQ894161 ABM85087 XM_011524079 XP_011522381 XR_934120 NM_004853 NP_004844 NR_033656 |
Function | Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits (By similarity). {ECO:0000250}. |
Tissue Specificity | Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
Top Pathways | SNARE interactions in vesicular transport |
Syntaxin 8 CRISPR/Cas9 KO Plasmid (h) - sc-405269 from Santa Cruz Biotechnology
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Syntaxin 8 HDR Plasmid (h) - sc-405269-HDR from Santa Cruz Biotechnology
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Syntaxin 8 Double Nickase Plasmid (h) - sc-405269-NIC from Santa Cruz Biotechnology
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Syntaxin 8 Double Nickase Plasmid (h2) - sc-405269-NIC-2 from Santa Cruz Biotechnology
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Syntaxin 8 CRISPR Activation Plasmid (h) - sc-405269-ACT from Santa Cruz Biotechnology
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Syntaxin 8 CRISPR Activation Plasmid (h2) - sc-405269-ACT-2 from Santa Cruz Biotechnology
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Syntaxin 8 Lentiviral Activation Particles (h) - sc-405269-LAC from Santa Cruz Biotechnology
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Syntaxin 8 Lentiviral Activation Particles (h2) - sc-405269-LAC-2 from Santa Cruz Biotechnology
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Syntaxin 8 siRNA (h) - sc-93822 from Santa Cruz Biotechnology
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Syntaxin 8 shRNA Plasmid (h) - sc-93822-SH from Santa Cruz Biotechnology
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Syntaxin 8 shRNA (h) Lentiviral Particles - sc-93822-V from Santa Cruz Biotechnology
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Syntaxin 8 RNAi - H00009482-R01 from Novus Biologicals
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MISSION® esiRNA - EHU039531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20790 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20790 from Sigma-Aldrich
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STX8 siRNA (Human) - CRH6297 from Cohesion Biosciences
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STX8 - MBS8221758 from MyBioSource
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shRNA set against Human STX8 (NM_004853.2) - SHH420420 from Creative biogene
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Human STX8 siRNA - orb266799 from Biorbyt
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STX8 shRNA Plasmid (Human) - CHH6297 from Cohesion Biosciences
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STX8 miRNA 3'UTR clone - MiUTR3H-06636 from Creative biogene
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