| Gene Symbol | STX8 |
|---|---|
| Entrez Gene | 9482 |
| Alt Symbol | CARB |
| Species | Human |
| Gene Type | protein-coding |
| Description | syntaxin 8 |
| Other Description | CIP-1-associated regulator of cyclin B|syntaxin-8 |
| Swissprots | Q53XT8 O60712 Q9UNK0 |
| Accessions | EAW90028 EAW90029 EAW90030 EAW90031 Q9UNK0 AF036715 AAC95285 AF062077 AAC36466 AF115323 AAD20831 BC009713 AAH09713 BC020924 BT007319 AAP35983 BU596252 DQ890985 ABM81911 DQ894161 ABM85087 XM_011524079 XP_011522381 XR_934120 NM_004853 NP_004844 NR_033656 |
| Function | Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. |
| Subcellular Location | Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Preferentially associated with the early endosome. To lesser extends, also present in late endosome, the plasma membrane and coated pits (By similarity). {ECO:0000250}. |
| Tissue Specificity | Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Top Pathways | SNARE interactions in vesicular transport |