| Gene Symbol |
PIGY
|
| Entrez Gene |
84992
|
| Alt Symbol |
PIG-Y
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol glycan anchor biosynthesis, class Y
|
| Other Description |
phosphatidylinositol N-acetylglucosaminyltransferase subunit Y|phosphatidylinositol-glycan biosynthesis class Y protein
|
| Swissprots |
Q3MUY2
|
| Accessions |
Q3MUY2 AB206972 BAE44507 BC007876 AAH07876 BI548853 DB519150 NM_001042616 NP_001036081
|
| Function |
Component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI- anchors for cell surface proteins. May act by regulating the catalytic subunit PIGA. {ECO:0000269|PubMed:16162815}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:16162815}; Multi-pass membrane protein {ECO:0000269|PubMed:16162815}.
|
| Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|