Gene Symbol | PIGY |
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Entrez Gene | 84992 |
Alt Symbol | PIG-Y |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class Y |
Other Description | phosphatidylinositol N-acetylglucosaminyltransferase subunit Y|phosphatidylinositol-glycan biosynthesis class Y protein |
Swissprots | Q3MUY2 |
Accessions | Q3MUY2 AB206972 BAE44507 BC007876 AAH07876 BI548853 DB519150 NM_001042616 NP_001036081 |
Function | Component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI- anchors for cell surface proteins. May act by regulating the catalytic subunit PIGA. {ECO:0000269|PubMed:16162815}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16162815}; Multi-pass membrane protein {ECO:0000269|PubMed:16162815}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-Y/preY CRISPR/Cas9 KO Plasmid (h) - sc-413756 from Santa Cruz Biotechnology
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PIG-Y/preY HDR Plasmid (h) - sc-413756-HDR from Santa Cruz Biotechnology
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PIG-Y/preY Double Nickase Plasmid (h) - sc-413756-NIC from Santa Cruz Biotechnology
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PIG-Y/preY Double Nickase Plasmid (h2) - sc-413756-NIC-2 from Santa Cruz Biotechnology
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PIG-Y/preY CRISPR Activation Plasmid (h) - sc-413756-ACT from Santa Cruz Biotechnology
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PIG-Y/preY CRISPR Activation Plasmid (h2) - sc-413756-ACT-2 from Santa Cruz Biotechnology
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PIG-Y/preY Lentiviral Activation Particles (h) - sc-413756-LAC from Santa Cruz Biotechnology
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PIG-Y/preY Lentiviral Activation Particles (h2) - sc-413756-LAC-2 from Santa Cruz Biotechnology
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PIG-Y siRNA (h) - sc-76137 from Santa Cruz Biotechnology
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PIG-Y shRNA Plasmid (h) - sc-76137-SH from Santa Cruz Biotechnology
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PIG-Y shRNA (h) Lentiviral Particles - sc-76137-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU106461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16802 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16802 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06635 from Sigma-Aldrich
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PIGY siRNA (Human) - CRJ3748 from Cohesion Biosciences
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PIGY shRNA Plasmid (Human) - CHJ3748 from Cohesion Biosciences
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PIGY miRNA 3'UTR clone - MiUTR3H-11398 from Creative biogene
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