| Gene Symbol |
SLC2A8
|
| Entrez Gene |
29988
|
| Alt Symbol |
GLUT8, GLUTX1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 2 (facilitated glucose transporter), member 8
|
| Other Description |
glucose transporter type 8|glucose transporter type X1|solute carrier family 2, facilitated glucose transporter member 8
|
| Swissprots |
Q9NSC4 Q8WUZ9 Q9NY64
|
| Accessions |
CBN63384 EAW87660 EAW87661 EAW87662 EAW87663 EAW87664 Q9NY64 AB209112 BAD92349 AF289587 AAL55771 AI818661 AJ245937 CAB75702 BC019043 AAH19043 BM044230 BX395379 DQ892909 ABM83835 DQ896160 ABM87159 HY025817 Y17801 CAB89809 XM_006717084 XP_006717147 XM_011518602 XP_011516904 XM_011518603 XP_011516905 XM_011518604 XP_011516906 XR_929783 NM_001271711 NP_001258640 NM_001271712 NP_001258641 NM_014580 NP_055395 NR_073416
|
| Function |
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
|