Gene Symbol | SLC2A8 |
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Entrez Gene | 29988 |
Alt Symbol | GLUT8, GLUTX1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 2 (facilitated glucose transporter), member 8 |
Other Description | glucose transporter type 8|glucose transporter type X1|solute carrier family 2, facilitated glucose transporter member 8 |
Swissprots | Q9NSC4 Q8WUZ9 Q9NY64 |
Accessions | CBN63384 EAW87660 EAW87661 EAW87662 EAW87663 EAW87664 Q9NY64 AB209112 BAD92349 AF289587 AAL55771 AI818661 AJ245937 CAB75702 BC019043 AAH19043 BM044230 BX395379 DQ892909 ABM83835 DQ896160 ABM87159 HY025817 Y17801 CAB89809 XM_006717084 XP_006717147 XM_011518602 XP_011516904 XM_011518603 XP_011516905 XM_011518604 XP_011516906 XR_929783 NM_001271711 NP_001258640 NM_001271712 NP_001258641 NM_014580 NP_055395 NR_073416 |
Function | Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration (By similarity). {ECO:0000250}. |
Tissue Specificity | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues. |
Glut8 CRISPR/Cas9 KO Plasmid (h) - sc-403183 from Santa Cruz Biotechnology
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Glut8 HDR Plasmid (h) - sc-403183-HDR from Santa Cruz Biotechnology
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Glut8 Double Nickase Plasmid (h) - sc-403183-NIC from Santa Cruz Biotechnology
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Glut8 Double Nickase Plasmid (h2) - sc-403183-NIC-2 from Santa Cruz Biotechnology
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Glut8 CRISPR Activation Plasmid (h) - sc-403183-ACT from Santa Cruz Biotechnology
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Glut8 CRISPR Activation Plasmid (h2) - sc-403183-ACT-2 from Santa Cruz Biotechnology
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Glut8 Lentiviral Activation Particles (h) - sc-403183-LAC from Santa Cruz Biotechnology
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Glut8 Lentiviral Activation Particles (h2) - sc-403183-LAC-2 from Santa Cruz Biotechnology
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Glut8 siRNA (h) - sc-35497 from Santa Cruz Biotechnology
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Glut8 shRNA Plasmid (h) - sc-35497-SH from Santa Cruz Biotechnology
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Glut8 shRNA (h) Lentiviral Particles - sc-35497-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU065021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19553 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19553 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05631 from Sigma-Aldrich
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SLC2A8 siRNA (Human) - CRH9317 from Cohesion Biosciences
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Glucose Transporter GLUT8 RNAi - H00029988-R01 from Novus Biologicals
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SLC2A8 - MBS8219091 from MyBioSource
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shRNA set against Human SLC2A8 (NM_014580.3) - SHH410328 from Creative biogene
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shRNA set against Human SLC2A8(NM_014580.3) - SHL006022 from Creative biogene
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Human SLC2A8 siRNA - orb269819 from Biorbyt
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SLC2A8 shRNA Plasmid (Human) - CHH9317 from Cohesion Biosciences
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SLC2A8 miRNA 3'UTR clone - MiUTR1H-09519 from Creative biogene
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