BSG

Gene Symbol BSG
Entrez Gene 682
Alt Symbol 5F7, CD147, EMMPRIN, M6, OK, TCSF
Species Human
Gene Type protein-coding
Description basigin (Ok blood group)
Other Description CD147 antigen|OK blood group antigen|basigin|collagenase stimulatory factor|extracellular matrix metalloproteinase inducer|leukocyte activation antigen M6|tumor cell-derived collagenase stimulatory factor
Swissprots Q7Z796 A6NJW1 Q8IZL7 D3YLG5 P35613
Accessions AAC33279 AAD10704 AAX20110 EAW61180 EAW61181 EAW61182 EAW61183 EAW61184 EAW61185 EAW61186 EAW61187 P35613 AB072923 BAB88938 AB085790 BAC76828 AB091680 BAC67168 AF548371 AAN40694 AK095912 AK296858 BAG59422 AK297880 BAG60203 AK302231 BAG63585 AY358113 AAQ88480 BC009040 AAH09040 BG480530 BI464857 BU501595 CB153773 D28441 BAA05807 D45131 BAA08109 DA007913 GU557064 ADD31881 GU557065 ADD31882 JF432780 ADZ15997 L10240 AAA68936 L20471 AAB41120 M87879 AAA91084 X64364 CAA45716 XM_005259619 XP_005259676 NM_001728 NP_001719 NM_198589 NP_940991 NM_198590 NP_940992 NM_198591 NP_940993
Function Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. {ECO:0000269|PubMed:17127621}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15946952}; Single-pass type I membrane protein {ECO:0000303|PubMed:15946952}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:17081065}.
Tissue Specificity Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.

Basigin/EMMPRIN (E1S1V) Rabbit mAb - 13287 from Cell Signaling Technology

Prices $250.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1S1V
Western blot analysis of extracts from various cell lines using Basigin/EMMPRIN (E1S1V) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

Basigin/EMMPRIN Antibody - 12314 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Basigin/EMMPRIN Antibody.

EMMPRIN (F-5) - sc-374101 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (F-5): sc-374101. Western blot analysis of EMMPRIN expression in SK-MEL-28 whole cell lysate.

EMMPRIN (UM-8D6) - sc-80545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (UM-8D6): sc-80545. Western blot analysis of EMMPRIN expression in HeLa (A) and A-431 (B) whole cell lysates.

EMMPRIN (A-12) - sc-25273 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (A-12): sc-25273. Western blot analysis of EMMPRIN expression in WI 38 whole cell lysate.

EMMPRIN (H-200) - sc-13976 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EMMPRIN (H-200): sc-13976. Western blot analysis of EMMPRIN expression in A-431 (A), SK-MEL-28 (B), WI 38 (C) and HeLa (D) whole cell lysates.

EMMPRIN (K-20) - sc-9753 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EMMPRIN (K-20): sc-9753. Western blot analysis of EMMPRIN expression in WI 38 whole cell lysate.

EMMPRIN (8D6) - sc-21746 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (8D6): sc-21746. Immunofluorescence staining of methanol-fixed T98G cells showing membrane staining.

EMMPRIN (N-19) - sc-9752 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EMMPRIN (N-19): sc-9752. Western blot analysis of EMMPRIN expression in A-431 (A), SK-MEL-28 (B) and WI-38 (C) whole cell lysates.

EMMPRIN (C-19) - sc-9754 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EMMPRIN (C-19): sc-9754. Western blot analysis of EMMPRIN expression in H4 whole cell lysate.

EMMPRIN (36.3G4) - sc-53582 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (36.3G4): sc-53582. Indirect FCM analysis of human peripheral blood leukocytes stained with EMMPRIN (36.3G4), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877

EMMPRIN (MEM-M6/1) - sc-51591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (MEM-M6/1): sc-51591. Indirect FCM analysis of human peripheral blood leukocytes stained with EMMPRIN (MEM-M6/1), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

EMMPRIN (1.BB.218) - sc-71038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (1.BB.218): sc-71038. Western blot analysis of EMMPRIN expression in SK-MEL-28 (A) and HeLa (B) whole cell lysates.

EMMPRIN (HIM6) - sc-53693 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
EMMPRIN (HIM6): sc-53693. Western blot analysis of EMMPRIN expression in Jurkat whole cell lysate.

Anti-CD147 antibody - ab64616 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of CD147 staining in human heart formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab64616,1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-CD147 antibody - ab70062 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD147 antibody (ab70062) at 1/500 dilutionLane 1 : extracts from HUVEC cellsLane 2 : extracts from HUVEC cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-CD147 antibody - ab11572 from Abcam

Prices $373.00
Sizes 25 µg
Host Goat
Clonality Polyclonal

Anti-CD147 antibody - ab88530 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
ab88530, at 10 µg/ml staining CD147 in paraformaldehyde fixed, permeabilised HeLa cells, by immunofluorescence.

Anti-CD147 antibody - ab155235 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD147 antibody (ab155235) at 1/500 dilutionLane 1 : non transfected 293T cell lysateLane 2 : CD147-transfected 293T cell lysatedeveloped using the ECL technique

Anti-CD147 antibody - ab124428 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD147 antibody (ab124428) at 1/1000 dilutionLane 1 : HeLa cell line lysateLane 2 : 293T cell line lysateLane 3 : Human fetal heart lysateLane 4 : Human fetal liver lysate

Anti-CD147 antibody - ab133876 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD147 antibody (ab133876) at 0.125 µg/ml + 721 B cell lysate at 10 µg

Anti-CD147 antibody [8D6] - ab194401 from Abcam

Host Mouse
Clonality Monoclonal
Clone 8D6

Anti-CD147 antibody [9B10] - ab119020 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9B10
All lanes : Anti-CD147 antibody [9B10] (ab119020) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY CD147 cDNALysates/proteins at 5 µg per lane.

Anti-CD147 antibody [AB1843] - ab49493 from Abcam

Prices $382.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone AB1843
Ab49493 at 1/20 dilution staining malignant cells of Human lung adenocarcinoma; paraffin embedded; used high temperature antigen unmasking technique.

Anti-CD147 antibody [CB43] - ab23907 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CB43
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