| Gene Symbol |
CARF
|
| Entrez Gene |
79800
|
| Alt Symbol |
ALS2CR8, NYD-SP24
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calcium responsive transcription factor
|
| Other Description |
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8|amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein|calcium-response factor|calcium-responsive transcription factor|testis development protein NYD-SP24
|
| Swissprots |
Q8N187 B4E1W7 Q96Q39 G3V1K7 Q96Q38 Q96J78 Q9H712 Q8WXC0 Q8ND29
|
| Accessions |
AAY24288 EAW70320 EAW70321 EAW70322 EAW70323 EAW70324 Q8N187 AB053309 BAB69018 AB053310 BAB69019 AF454946 AAL62330 AK022737 AK025232 BAB15088 AK225218 AK295499 BAG58419 AK295703 BAG58550 AK299366 BAG61358 AK304014 BAG64929 AK308171 AK310640 AK316432 BAH14803 AL834188 CAD38882 AV751848 AY032876 AAK66819 BC021999 BC033777 AAH33777 CK825814 DA405623 DB094349 DQ891348 ABM82274 DQ894528 ABM85454 XM_005246858 XP_005246915 XM_005246859 XP_005246916 XM_005246860 XP_005246917 XM_005246863 XP_005246920 XM_005246864 XP_005246921 XM_006712757 XP_006712820 XM_006712759 XP_006712822 XM_006712760 XP_006712823 XM_011511867 XP_011510169 XM_011511868 XP_011510170 XM_011511869 XP_011510171 NM_001104586 NP_001098056 NM_001282910 NP_001269839 NM_001282911 NP_001269840 NM_001282912 NP_001269841 NM_024744 NP_079020
|
| Function |
Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence. {ECO:0000269|PubMed:11832226, ECO:0000269|PubMed:22174809}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
![Western Blot: ALS2CR8 Overexpression Lysate [H00079800-T01] - Lane 1: ALS2CR8 transfected lysate (79.09 KDa) Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26648_ALS2CR8%2520Overexpression%2520Lysate-Western%2520Blot-H00079800-T01-img0001.jpg)