Gene Symbol | CRX |
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Entrez Gene | 1406 |
Alt Symbol | CORD2, CRD, LCA7, OTX3 |
Species | Human |
Gene Type | protein-coding |
Description | cone-rod homeobox |
Other Description | cone-rod homeobox protein|orthodenticle homeobox 3 |
Swissprots | O43186 Q0QD45 |
Accessions | AAB88418 EAW57515 O43186 AF335247 AF335249 AF335593 AF335594 AF335595 AF442496 AL711350 BC009045 BC016664 AAH16664 BC053672 AAH53672 BT007364 AAP36028 BU736672 DQ340179 ABC69290 DQ426867 DQ426868 ABD90533 DQ893564 ABM84490 DQ894239 ABM85165 EF432655 ABO31091 NM_000554 NP_000545 |
Function | Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. {ECO:0000269|PubMed:10625658}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
Tissue Specificity | Retina. |
CRX (A-9) - sc-377138 from Santa Cruz Biotechnology
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CRX (A-14) - sc-22380 from Santa Cruz Biotechnology
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CRX (B-11) - sc-377207 from Santa Cruz Biotechnology
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CRX (G-18) - sc-22381 from Santa Cruz Biotechnology
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CRX (H-120) - sc-30150 from Santa Cruz Biotechnology
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CRX (Q17) - sc-81958 from Santa Cruz Biotechnology
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Anti-CORD2 antibody - ab54635 from Abcam
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Anti-CORD2 antibody - ab151477 from Abcam
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Anti-CORD2 antibody [EPR9582] - ab140603 from Abcam
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Anti-TPRX2P antibody - ab186212 from Abcam
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Anti-CRD / CRX Antibody - LS-C341823 from LifeSpan Bioscience
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Anti-CRD / CRX Antibody - LS-C335596 from LifeSpan Bioscience
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Anti-CRD / CRX Antibody (aa23-72) - LS-C201320 from LifeSpan Bioscience
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Anti-CRD / CRX Antibody (aa294-297) - LS-C344245 from LifeSpan Bioscience
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Anti-CRD / CRX Antibody (clone F6-C2) - LS-C196968 from LifeSpan Bioscience
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Anti-CRD / CRX Antibody (C-Terminus) - LS-C204995 from LifeSpan Bioscience
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CRX/CORD2 Antibody - AF7085 from Novus Biologicals
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CRX/CORD2 Antibody - NBP1-88059 from Novus Biologicals
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CRX/CORD2 Antibody (4G11) - H00001406-M02 from Novus Biologicals
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CRX/CORD2 Antibody (F6-C2) - H00001406-M01 from Novus Biologicals
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CRX/CORD2 Antibody - NBP1-88060 from Novus Biologicals
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CRX/CORD2 Antibody (4A12) - H00001406-M06 from Novus Biologicals
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CRX/CORD2 Antibody (6D11) - H00001406-M04 from Novus Biologicals
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CRX/CORD2 Antibody (2F12) - H00001406-M03 from Novus Biologicals
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CRX/CORD2 Antibody - NBP2-15964 from Novus Biologicals
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