CRX

Gene Symbol CRX
Entrez Gene 1406
Alt Symbol CORD2, CRD, LCA7, OTX3
Species Human
Gene Type protein-coding
Description cone-rod homeobox
Other Description cone-rod homeobox protein|orthodenticle homeobox 3
Swissprots O43186 Q0QD45
Accessions AAB88418 EAW57515 O43186 AF335247 AF335249 AF335593 AF335594 AF335595 AF442496 AL711350 BC009045 BC016664 AAH16664 BC053672 AAH53672 BT007364 AAP36028 BU736672 DQ340179 ABC69290 DQ426867 DQ426868 ABD90533 DQ893564 ABM84490 DQ894239 ABM85165 EF432655 ABO31091 NM_000554 NP_000545
Function Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. {ECO:0000269|PubMed:10625658}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity Retina.

CRX CRISPR/Cas9 KO Plasmid (h) - sc-401736 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX HDR Plasmid (h) - sc-401736-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX Double Nickase Plasmid (h) - sc-401736-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX Double Nickase Plasmid (h2) - sc-401736-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX CRISPR Activation Plasmid (h) - sc-401736-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX CRISPR Activation Plasmid (h2) - sc-401736-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX Lentiviral Activation Particles (h) - sc-401736-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX Lentiviral Activation Particles (h2) - sc-401736-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRX siRNA (h) - sc-38649 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRX shRNA Plasmid (h) - sc-38649-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRX shRNA (h) Lentiviral Particles - sc-38649-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRX/CORD2 RNAi - H00001406-R01V from Novus Biologicals

Category siRNA
Prices $629.00
Sizes 20 nmol
Species Reactivities Human
Western blot analysis of CRX over-expressed 293 cell line, cotransfected with CRX Validated Chimera RNAi or non-transfected control. Blot probed with H00001406-M01. GAPDH (36.1 kDa) used as loading control.

MISSION® esiRNA - EHU005741 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6600 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6600 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CRX siRNA (Human) - CRH0988 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRX/CORD2 RNAi - H00001406-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CRX - MBS8226942 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRX (NM_000554.4) - SHH269853 from Creative biogene

Category siRNA
Species Reactivities Human

CRX shRNA Plasmid (Human) - CHH0988 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRX miRNA 3'UTR clone - MiUTR4H-TG02367 from Creative biogene

Species Reactivities Human
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