Gene Symbol |
SLC10A1
|
Entrez Gene |
6554
|
Alt Symbol |
NTCP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 10 (sodium/bile acid cotransporter), member 1
|
Other Description |
Na(+)/bile acid cotransporter|Na(+)/taurocholate transport protein|Na/taurocholate cotransporting polypeptide|cell growth-inhibiting gene 29 protein|growth-inhibiting protein 29|sodium/bile acid cotransporter|sodium/taurocholate cotransporter|sodium/taurocholate cotransporting polypeptide|solute carrier family 10 (sodium/bile acid cotransporter family), member 1|solute carrier family 10 member 1
|
Swissprots |
B9EGB6 Q2TU29 Q14973
|
Accessions |
AAD56541 EAW81011 Q14973 AK314028 BAG36738 AY544127 AAT11158 BC069799 AAH69799 BC069822 AAH69822 BC074724 AAH74724 BC126298 AAI26299 BC136355 AAI36356 HQ258189 ADR82943 HQ447437 ADQ31923 JQ814895 AFL02669 L21893 AAA36381 NM_003049 NP_003040
|
Function |
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Top Pathways |
Bile secretion
|