Gene Symbol | SLC10A1 |
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Entrez Gene | 6554 |
Alt Symbol | NTCP |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
Other Description | Na(+)/bile acid cotransporter|Na(+)/taurocholate transport protein|Na/taurocholate cotransporting polypeptide|cell growth-inhibiting gene 29 protein|growth-inhibiting protein 29|sodium/bile acid cotransporter|sodium/taurocholate cotransporter|sodium/taurocholate cotransporting polypeptide|solute carrier family 10 (sodium/bile acid cotransporter family), member 1|solute carrier family 10 member 1 |
Swissprots | B9EGB6 Q2TU29 Q14973 |
Accessions | AAD56541 EAW81011 Q14973 AK314028 BAG36738 AY544127 AAT11158 BC069799 AAH69799 BC069822 AAH69822 BC074724 AAH74724 BC126298 AAI26299 BC136355 AAI36356 HQ258189 ADR82943 HQ447437 ADQ31923 JQ814895 AFL02669 L21893 AAA36381 NM_003049 NP_003040 |
Function | The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | Bile secretion |
NTCP CRISPR/Cas9 KO Plasmid (h) - sc-400840 from Santa Cruz Biotechnology
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NTCP HDR Plasmid (h) - sc-400840-HDR from Santa Cruz Biotechnology
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NTCP Double Nickase Plasmid (h) - sc-400840-NIC from Santa Cruz Biotechnology
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NTCP Double Nickase Plasmid (h2) - sc-400840-NIC-2 from Santa Cruz Biotechnology
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NTCP CRISPR Activation Plasmid (h) - sc-400840-ACT from Santa Cruz Biotechnology
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NTCP CRISPR Activation Plasmid (h2) - sc-400840-ACT-2 from Santa Cruz Biotechnology
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NTCP Lentiviral Activation Particles (h) - sc-400840-LAC from Santa Cruz Biotechnology
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NTCP Lentiviral Activation Particles (h2) - sc-400840-LAC-2 from Santa Cruz Biotechnology
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NTCP siRNA (h) - sc-92260 from Santa Cruz Biotechnology
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NTCP shRNA Plasmid (h) - sc-92260-SH from Santa Cruz Biotechnology
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NTCP shRNA (h) Lentiviral Particles - sc-92260-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU038961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19396 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19396 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03725 from Sigma-Aldrich
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SLC10A1 siRNA (Human) - CRH4444 from Cohesion Biosciences
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SLC10A1 RNAi - H00006554-R01 from Novus Biologicals
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SLC10A1 - MBS8205230 from MyBioSource
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shRNA set against Human Slc10a1 (NM_003049.3) - SHH408192 from Creative biogene
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Human SLC10A1 siRNA - orb264946 from Biorbyt
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SLC10A1 shRNA Plasmid (Human) - CHH4444 from Cohesion Biosciences
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SLC10A1 miRNA 3'UTR clone - MiUTR3H-02118 from Creative biogene
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