CFL2

Gene Symbol	CFL2
Entrez Gene	1073
Alt Symbol	NEM7
Species	Human
Gene Type	protein-coding
Description	cofilin 2 (muscle)
Other Description	cofilin, muscle isoform|cofilin-2|nemaline myopathy type 7
Swissprots	Q9Y281 G3V5P4
Accessions	AAF64498 AAF97934 EAW65908 EAW65910 EAW65911 EAW65912 Q9Y281 AF087867 AAM10495 AF134802 AAD31280 AF134803 AAD31281 AI754134 AK314157 BAG36842 AL117457 AL599958 BC011444 AAH11444 BC022364 AAH22364 BC022876 AAH22876 BC025683 CB992605 DA298739 DA897112 DB378917 EU832642 ACE87733 EU832719 ACE87051 XM_011536363 XP_011534665 NM_001243645 NP_001230574 NM_021914 NP_068733 NM_138638 NP_619579 NR_028130 NR_028131
Function	Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity	Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Top Pathways	Axon guidance, Fc gamma R-mediated phagocytosis, Pertussis, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cofilin 2 peptide (142-152) - ab45798 from Abcam Category Peptide Prices $290.00 Sizes 100 µg Species Human

Human Cofilin 2 full length protein - ab114614 from Abcam Category Protein Source Wheat germ Species Human

Human Cofilin 2 full length protein - ab111635 from Abcam Category Protein Source E. coli Species Human

CFL2 / Cofilin 2 Antibody Blocking Peptide - LS-E2986 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CFL2 / Cofilin 2 Antibody Blocking Peptide - LS-E25930 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CFL2 / Cofilin 2 Antibody Blocking Peptide - LS-E17521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Cofilin 2 Protein - H00001073-P01 from Novus Biologicals Category Protein Prices $529.00 Sizes 25 µg Source Wheat Germ Species Human

Cofilin 2 Partial Recombinant Protein - H00001073-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Cofilin 2 Protein - NBP1-72427 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CFL2-Antibody-N-term-Blocking-peptide - BP14117a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cofilin 2 blocking peptide - GTX89482-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

Human CFL2 protein (His Tag) - orb138537 from Biorbyt Category Protein Prices $298.00, $434.00 Sizes 20 μg, 50 μg Source E. coli Species Human

Human CFL2 protein - orb168103 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CFL2 protein (His tag) - 80R-1943 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Human Cofilin 2, Muscle Protein - abx065991 from Abbexa Category Protein Source E.coli Species Human

Cofilin 2 Peptide - AC21-0759-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Cofilin-2 (1-166, His-tag) - AR39125PU-L from Acris Antibodies Category Protein Prices $785.00 Sizes 500 µg Source E. coli Species Human

Cofilin-2 (1-166, His-tag) - AR39125PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Cofilin-2 - H00001073-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Cofilin-2 - H00001073-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Cofilin-2 - H00001073-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Cofilin-2 - H00001073-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Cofilin-2, Human Recombinant - 228-13351-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Cofilin-2 - 228-13351-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Cofilin-2 - 228-13351-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

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