CFL2

Gene Symbol CFL2
Entrez Gene 1073
Alt Symbol NEM7
Species Human
Gene Type protein-coding
Description cofilin 2 (muscle)
Other Description cofilin, muscle isoform|cofilin-2|nemaline myopathy type 7
Swissprots Q9Y281 G3V5P4
Accessions AAF64498 AAF97934 EAW65908 EAW65910 EAW65911 EAW65912 Q9Y281 AF087867 AAM10495 AF134802 AAD31280 AF134803 AAD31281 AI754134 AK314157 BAG36842 AL117457 AL599958 BC011444 AAH11444 BC022364 AAH22364 BC022876 AAH22876 BC025683 CB992605 DA298739 DA897112 DB378917 EU832642 ACE87733 EU832719 ACE87051 XM_011536363 XP_011534665 NM_001243645 NP_001230574 NM_021914 NP_068733 NM_138638 NP_619579 NR_028130 NR_028131
Function Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity). {ECO:0000250}.
Subcellular Location Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Top Pathways Axon guidance, Fc gamma R-mediated phagocytosis, Pertussis, Regulation of actin cytoskeleton

Cofilin 2 CRISPR/Cas9 KO Plasmid (h) - sc-401512 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 HDR Plasmid (h) - sc-401512-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 Double Nickase Plasmid (h) - sc-401512-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 Double Nickase Plasmid (h2) - sc-401512-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 CRISPR Activation Plasmid (h) - sc-401512-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 CRISPR Activation Plasmid (h2) - sc-401512-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 Lentiviral Activation Particles (h) - sc-401512-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 Lentiviral Activation Particles (h2) - sc-401512-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cofilin 2 siRNA (h) - sc-37027 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cofilin 2 shRNA Plasmid (h) - sc-37027-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cofilin 2 shRNA (h) Lentiviral Particles - sc-37027-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cofilin 2 RNAi - H00001073-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Cofilin 2 RNAi - H00001073-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU061971 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6007 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6007 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CFL2 siRNA (Human) - CRH0774 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CFL2 - MBS8240048 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CFL2 (NM_138638.4) - SHH262493 from Creative biogene

Category siRNA
Species Reactivities Human

CFL2 shRNA Plasmid (Human) - CHH0774 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CFL2 miRNA 3'UTR clone - MiUTR4H-TG10881 from Creative biogene

Species Reactivities Human
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