GPR161

Gene Symbol	GPR161
Entrez Gene	23432
Alt Symbol	RE2
Species	Human
Gene Type	protein-coding
Description	G protein-coupled receptor 161
Other Description	G-protein coupled receptor 161|G-protein coupled receptor RE2
Swissprots	Q5TGK1 F5GXD6 B7Z5E8 Q5TGK0 O75963 Q8N6U8 Q5TGK2 F5H6J7 B7Z5Z6 B3KV34 B7Z5D7
Accessions	EAW90818 EAW90819 Q8N6U8 AA662800 AF091890 AAC61598 AK026059 AK056040 BAG51611 AK091271 BAC03624 AK091869 AK095302 AK122656 BAG53646 AK298797 BAH12873 AK298850 BAH12884 AK299634 BAH13082 AK310019 AY275468 AAP32300 BC028163 AAH28163 DQ893369 ABM84295 DQ896689 ABM87688 XM_005245055 XP_005245112 XM_005245056 XP_005245113 XM_005245057 XP_005245114 XM_006711251 XP_006711314 XM_006711252 XP_006711315 XM_006711253 XP_006711316 XM_011509370 XP_011507672 XM_011509371 XP_011507673 XM_011509372 XP_011507674 XM_011509373 XP_011507675 XM_011509374 XP_011507676 XM_011509375 XP_011507677 XM_011509376 XP_011507678 XM_011509377 XP_011507679 XM_011509378 XP_011507680 NM_007369 NM_001267609 NP_001254538 NM_001267610 NP_001254539 NM_001267611 NP_001254540 NM_001267612 NP_001254541 NM_001267613 NP_001254542 NM_001267614 NP_001254543 NM_153832 NP_722561
Function	Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity). {ECO:0000250}.
Subcellular Location	Cell projection, cilium membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Mainly localizes to primary cilium in a TULP3 and IFT-A complex-dependent manner. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes and is apparently not degraded (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GPR161 protein fragment - ab161641 from Abcam Category Protein Source Wheat germ Species Human

GPR161 Antibody Blocking Peptide - LS-E28723 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR161 Antibody Blocking Peptide - LS-E28721 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR161 Antibody Blocking Peptide - LS-E28724 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR161 Antibody Blocking Peptide - LS-E15728 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR161 Antibody Blocking Peptide - LS-E15583 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR161 Antibody Blocking Peptide - LS-E15584 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GPR161 Protein - H00023432-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GPR161 Protein - H00023432-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

Human GPR161 protein - orb245201 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

GPR161 Blocking Peptide - 33R-2995 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR161 Blocking Peptide - 33R-6464 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR161 Blocking Peptide - 33R-4076 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR161 Blocking Peptide - 33R-8538 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPR161 - H00023432-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

GPR161 - H00023432-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GPR161 - H00023432-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GPR161 fusion protein - ag4221 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant human G-protein coupled receptor 161 protein - CSB-EP041144h CSB-BP041144h CSB-MP041144h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human G-protein coupled receptor 161(GPR161),partial - CSB-RP041144h from Cusabio Category Protein Source E.coli Species Human

GPR161 Recombinant Protein Antigen - NBP1-87146PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GPR161 Peptide, Human - M34GP06547H from Creative Peptides Category Peptide Source Synthetic. Species Human

G-protein coupled receptor 161, Recombinant Protein - MBS717231 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli

G-protein coupled receptor 161 (GPR161), Recombinant Protein - MBS7016130 from MyBioSource Category Protein Prices $1,325.00, $2,310.00, $3,520.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant human G-protein coupled receptor 161 - AP71844 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Search more