| Gene Symbol |
MTMR4
|
| Entrez Gene |
9110
|
| Alt Symbol |
FYVE-DSP2, ZFYVE11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myotubularin related protein 4
|
| Other Description |
FYVE domain-containing dual specificity protein phosphatase 2|myotubularin-related protein 4|zinc finger FYVE domain-containing protein 11|zinc finger, FYVE domain containing 11
|
| Swissprots |
Q9NYA4 Q8IV27 Q9Y4D5 D3DTZ6
|
| Accessions |
EAW94454 EAW94455 Q9NYA4 AB014547 BAA31622 AF264717 AAF72539 AI538945 AK308877 BC035609 AAH35609 DR003190 XM_005257784 XP_005257841 XM_005257785 XP_005257842 XM_005257786 XP_005257843 XM_006722168 XP_006722231 XM_011525460 XP_011523762 NM_004687 NP_004678
|
| Function |
Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3). {ECO:0000269|PubMed:11302699}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11302699}. Membrane {ECO:0000269|PubMed:11302699}; Peripheral membrane protein {ECO:0000269|PubMed:11302699}. Note=Localized to perinuclear region.
|
| Tissue Specificity |
Expressed in brain, heart, kidney, spleen, liver, colon, testis, muscle, placenta, thyroid gland, pancreas, ovary, prostate, skin, peripheral blood, and bone marrow. {ECO:0000269|PubMed:11302699}.
|