| Gene Symbol |
DYNAP
|
| Entrez Gene |
284254
|
| Alt Symbol |
C18orf26
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynactin associated protein
|
| Other Description |
dynactin-associated protein|full
|
| Swissprots |
Q8N1N2
|
| Accessions |
EAW63007 Q8N1N2 AK096425 BAC04784 XM_011525923 XP_011524225 XM_011525924 XP_011524226 XM_011525925 XP_011524227 XM_011525926 XP_011524228 NM_001307955 NP_001294884 NM_173629 NP_775900
|
| Function |
Plays a role in the regulation of cell proliferation. Promotes activation of the AKT1 signaling pathway. Promotes phosphorylation of AKT1 at 'Ser-473'. {ECO:0000269|PubMed:20978158}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:20978158}; Single-pass membrane protein {ECO:0000269|PubMed:20978158}. Cell membrane {ECO:0000269|PubMed:20978158}; Single-pass membrane protein {ECO:0000269|PubMed:20978158}. Note=Concentrated at cell-cell borders. Localizes at membranes in a microtubule-dependent manner.
|
| Tissue Specificity |
Expressed in fibroblast and numerous cancer cell lines (at protein level). {ECO:0000269|PubMed:20978158}.
|