Gene Symbol | DYNAP |
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Entrez Gene | 284254 |
Alt Symbol | C18orf26 |
Species | Human |
Gene Type | protein-coding |
Description | dynactin associated protein |
Other Description | dynactin-associated protein|full |
Swissprots | Q8N1N2 |
Accessions | EAW63007 Q8N1N2 AK096425 BAC04784 XM_011525923 XP_011524225 XM_011525924 XP_011524226 XM_011525925 XP_011524227 XM_011525926 XP_011524228 NM_001307955 NP_001294884 NM_173629 NP_775900 |
Function | Plays a role in the regulation of cell proliferation. Promotes activation of the AKT1 signaling pathway. Promotes phosphorylation of AKT1 at 'Ser-473'. {ECO:0000269|PubMed:20978158}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000269|PubMed:20978158}; Single-pass membrane protein {ECO:0000269|PubMed:20978158}. Cell membrane {ECO:0000269|PubMed:20978158}; Single-pass membrane protein {ECO:0000269|PubMed:20978158}. Note=Concentrated at cell-cell borders. Localizes at membranes in a microtubule-dependent manner. |
Tissue Specificity | Expressed in fibroblast and numerous cancer cell lines (at protein level). {ECO:0000269|PubMed:20978158}. |
C18orf26 CRISPR/Cas9 KO Plasmid (h) - sc-415359 from Santa Cruz Biotechnology
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C18orf26 HDR Plasmid (h) - sc-415359-HDR from Santa Cruz Biotechnology
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C18orf26 Double Nickase Plasmid (h) - sc-415359-NIC from Santa Cruz Biotechnology
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C18orf26 Double Nickase Plasmid (h2) - sc-415359-NIC-2 from Santa Cruz Biotechnology
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C18orf26 CRISPR Activation Plasmid (h) - sc-415359-ACT from Santa Cruz Biotechnology
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C18orf26 CRISPR Activation Plasmid (h2) - sc-415359-ACT-2 from Santa Cruz Biotechnology
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C18orf26 Lentiviral Activation Particles (h) - sc-415359-LAC from Santa Cruz Biotechnology
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C18orf26 Lentiviral Activation Particles (h2) - sc-415359-LAC-2 from Santa Cruz Biotechnology
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C18orf26 siRNA (h) - sc-72680 from Santa Cruz Biotechnology
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C18orf26 shRNA Plasmid (h) - sc-72680-SH from Santa Cruz Biotechnology
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C18orf26 shRNA (h) Lentiviral Particles - sc-72680-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU031171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4508 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4508 from Sigma-Aldrich
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DYNAP siRNA (Human) - CRJ6985 from Cohesion Biosciences
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DYNAP - MBS8219461 from MyBioSource
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shRNA set against Human C18orf26 (NM_173629.1) - SHH250038 from Creative biogene
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DYNAP shRNA Plasmid (Human) - CHJ6985 from Cohesion Biosciences
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DYNAP miRNA 3'UTR clone - MiUTR1H-01186 from Creative biogene
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