Gene Symbol | DIO2 |
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Entrez Gene | 1734 |
Alt Symbol | 5DII, D2, DIOII, SelY, TXDI2 |
Species | Human |
Gene Type | protein-coding |
Description | deiodinase, iodothyronine, type II |
Other Description | deiodinase-2|deiodonase-2|thyroxine deiodinase, type II|type 2 DI|type 2 iodothyronine deiodinase|type II iodothyronine deiodinase|type-II 5'-deiodinase|type-II 5'deiodinase |
Swissprots | Q6B0A3 Q9UDZ1 Q9P1W4 G3V315 Q92813 Q9HCP8 B9EGK0 |
Accessions | AAD45494 AAF37612 BAB21594 EAW81320 EAW81321 EAW81322 EAW81323 EAW81324 EAW81325 Q92813 AB041843 BAB16838 AB041844 BAB16839 AF007144 AF093774 AAC95470 AF123661 AI248279 AI697311 AI701403 AI888658 AK292210 BAF84899 AK311603 BC063118 AAH63118 BC074882 AAH74882 BC136514 AAI36515 BF224328 CD691767 CD701270 U53506 AAC50663 NM_000793 NP_000784 NM_001007023 NP_001007024 NM_001242502 NP_001229431 NM_001242503 NP_001229432 NM_013989 NP_054644 |
Function | Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. |
DIO2 peptide - ab131396 from Abcam
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DIO2 peptide - ab87369 from Abcam
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Human DIO2 peptide - ab87528 from Abcam
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Human DIO2 protein fragment - ab152331 from Abcam
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DIO2 Antibody Blocking Peptide - LS-E26270 from LifeSpan Bioscience
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DIO2 Antibody Blocking Peptide - LS-E9741 from LifeSpan Bioscience
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Recombinant Human DIO2 Protein - H00001734-Q01 from Novus Biologicals
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DIO2-Antibody-Center-Blocking-Peptide - BP8718c from Abgent, a WuXi AppTec company
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DIO2 blocking peptide - GTX89019-PEP from GeneTex
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DIO2 Peptide - AC21-1102-P from Abcore
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DIO2 - H00001734-Q01-10 from Acris Antibodies
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DIO2 - H00001734-Q01-25 from Acris Antibodies
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DIO2 Peptide - 46-651P from ProSci
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DIO2 fusion protein - ag12266 from Proteintech Group
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Recombinant Human DIO2 - DIO2-532H from Creative Biomart
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Recombinant Deiodinase, Iodothyronine, Type II (DIO2) - RPC903Hu01 from Uscn Life Science Inc.
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Recombinant Deiodinase, Iodothyronine, Type II (DIO2) - RPC903Mu01 from Uscn Life Science Inc.
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Recombinant Deiodinase, Iodothyronine, Type II (DIO2) - RPC903Mu02 from Uscn Life Science Inc.
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Recombinant Deiodinase, Iodothyronine, Type II (DIO2) - RPC903Ra01 from Uscn Life Science Inc.
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Recombinant Deiodinase, Iodothyronine, Type II (DIO2) - RPC903Hu01 from Cloud-clone
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Recombinant Aquifex aeolicus NADH-quinone oxidoreductase subunit C/D 2(nuoC2) , - CSB-YP526587DNV CSB-EP526587DNV CSB-BP526587DNV CSB-MP526587DNV from Cusabio
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Recombinant Protein D2(D2) - CSB-YP347477OEG CSB-EP347477OEG CSB-BP347477OEG CSB-MP347477OEG from Cusabio
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Recombinant Lithobates catesbeiana Type II iodothyronine deiodinase(dio2) - CSB-YP341846LQA CSB-EP341846LQA CSB-BP341846LQA CSB-MP341846LQA from Cusabio
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DIO2, Peptide - MBS425448 from MyBioSource
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DIO2 Protein - NBP1-80770PEP from Novus Biologicals
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