| Gene Symbol |
MED10
|
| Entrez Gene |
84246
|
| Alt Symbol |
L6, NUT2, TRG20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 10
|
| Other Description |
TRG-17|TRG-20|mediator of RNA polymerase II transcription subunit 10|mediator of RNA polymerase II transcription, subunit 10|transformation-related gene 17 protein|transformation-related gene 20 protein
|
| Swissprots |
C6G491 Q9BTT4
|
| Accessions |
ACS13739 EAX08110 Q9BTT4 AA648258 AK075493 AY277599 AAQ18038 AY453397 AAS47514 AY598325 AAT06736 BC003353 AAH03353 BI597082 NM_032286 NP_115662
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
![Western Blot: MED10 Overexpression Lysate (Adult Normal) [NBL1-12979] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MED10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7130_MED10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12979-img0002.jpg)