| Gene Symbol |
OXCT2
|
| Entrez Gene |
64064
|
| Alt Symbol |
FKSG25, SCOTT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
3-oxoacid CoA transferase 2
|
| Other Description |
3-oxoacid CoA-transferase 2A|3-oxoacid-CoA transferase 2A|succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial|succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial|testis-specific succinyl CoA:3-oxoacid CoA-transferase|testis-specific succinyl-CoA:3-oxoacid CoA-transferase
|
| Swissprots |
Q9H1I4 Q5QPK4 Q8NHR1 Q9BYC2 B2RBB4
|
| Accessions |
CBH19406 Q9BYC2 AB050193 BAB40810 AK024440 BAB15730 AK093089 BAG52651 AK314586 BAG37161 AY013700 AAG33922 BC030015 BC072388 AAH72388 DQ893340 ABM84266 DQ896660 ABM87659 NM_022120 NP_071403
|
| Function |
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:11756565}.
|
| Tissue Specificity |
Testis specific. {ECO:0000269|PubMed:11756565}.
|
| Top Pathways |
Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism
|