LRR1

Gene Symbol LRR1
Entrez Gene 122769
Alt Symbol 4-1BBLRR, LRR-1, PPIL5
Species Human
Gene Type protein-coding
Description leucine rich repeat protein 1
Other Description 4-1BB-mediated signaling molecule|4-1BB-mediated-signaling molecule|LRR-repeat protein 1|cyclophilin-like 5|leucine-rich repeat protein 1|peptidylprolyl isomerase (cyclophilin)-like 5|peptidylprolyl isomerase-like 5
Swissprots Q52M24 Q86SZ1 B4DDE0 Q96L50 Q8N6H9 A5D6X3
Accessions EAW65761 EAW65762 EAW65763 EAW65764 Q96L50 AA742244 AK293156 BAG56701 AY052405 AAL11430 BC030142 AAH30142 BC064133 AAH64133 BC093697 AAH93697 BC107888 AAI07889 BC112241 AAI12242 BC139921 AAI39922 BC146425 AAI46426 BC148859 AAI48860 BI825814 BI826606 BI829295 BQ059807 BX248298 CAD62625 BX648029 CAH10374 DQ892269 ABM83195 DQ895470 ABM86396 NM_152329 NP_689542 NM_203467 NP_982292 NR_037792 NR_037793 NM_203466
Function May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:15601820}.
Tissue Specificity Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.

PPIL5 CRISPR/Cas9 KO Plasmid (h) - sc-410270 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 HDR Plasmid (h) - sc-410270-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 Double Nickase Plasmid (h) - sc-410270-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 Double Nickase Plasmid (h2) - sc-410270-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 CRISPR Activation Plasmid (h) - sc-410270-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 CRISPR Activation Plasmid (h2) - sc-410270-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 Lentiviral Activation Particles (h) - sc-410270-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 Lentiviral Activation Particles (h2) - sc-410270-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPIL5 siRNA (h) - sc-92289 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPIL5 shRNA Plasmid (h) - sc-92289-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPIL5 shRNA (h) Lentiviral Particles - sc-92289-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU074751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17235 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17235 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LRR1 siRNA (Human) - CRJ4710 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LRR1 (NM_152329.3) - SHH334119 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PPIL5(NM_152329.3) - SHR132450 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PPIL5(NM_203467.1) - SHR132504 from Creative biogene

Category siRNA
Species Reactivities Human

Human LRR1 siRNA - orb275211 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LRR1 shRNA Plasmid (Human) - CHJ4710 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LRR1 miRNA 3'UTR clone - MiUTR1H-08160 from Creative biogene

Species Reactivities Human

LRR1 miRNA 3'UTR clone - MiUTR1H-08161 from Creative biogene

Species Reactivities Human
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