Gene Symbol | PRPF40A |
---|---|
Entrez Gene | 55660 |
Alt Symbol | FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40 |
Species | Human |
Gene Type | protein-coding |
Description | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) |
Other Description | Fas-ligand associated factor 1|Huntingtin-interacting protein A|NY-REN-6 antigen|fas ligand-associated factor 1|formin binding protein 3|formin-binding protein 11|huntingtin yeast partner A|huntingtin-interacting protein 10|pre-mRNA-processing factor 40 homolog A|renal carcinoma antigen NY-REN-6 |
Swissprots | O75400 Q9P0Q2 Q9NWU9 O43856 Q9Y5A8 Q8TBQ1 O75404 Q9H782 |
Accessions | AAX88960 EAX11482 O75400 AF049523 AAC27501 AF049524 AAC27502 AF049528 AAC27506 AF151059 AAF36145 AF155096 AAD42862 AK000592 BAA91277 AK021621 AK024810 BAB15016 AK298547 BAG60744 AK315187 BAG37627 BC000273 BC011788 AAH11788 BC027178 AAH27178 BC029414 AAH29414 BC073138 BU753487 EG328171 U70667 AAB93495 XM_005246676 XP_005246733 XM_005246677 XP_005246734 XM_005246678 XP_005246735 XM_011511446 XP_011509748 XM_011511447 XP_011509749 XM_011511448 XP_011509750 XM_011511449 XP_011509751 NM_017892 NP_060362 |
Function | Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. {ECO:0000250, ECO:0000269|PubMed:21834987}. |
Subcellular Location | Nucleus speckle {ECO:0000250}. Nucleus matrix {ECO:0000269|PubMed:16391387}. Note=Colocalizes with AKAP8L in the nuclear matrix. {ECO:0000250}. |
Tissue Specificity | Expressed in the brain cortex (at protein level). Widely expressed. {ECO:0000269|PubMed:16391387, ECO:0000269|PubMed:9700202}. |
Top Pathways | Spliceosome |
FNBP3 (D-20) - sc-68080 from Santa Cruz Biotechnology
|
||||||||
FNBP3 (E-16) - sc-68081 from Santa Cruz Biotechnology
|
||||||||
Anti-FNBP3 antibody - ab88463 from Abcam
|
||||||||
Anti-FNBP3 antibody - ab13774 from Abcam
|
||||||||
Anti-PRPF40A / FNBP3 Antibody (aa851-900) - LS-C145781 from LifeSpan Bioscience
|
||||||||
FNBP3 Antibody - NBP1-87933 from Novus Biologicals
|
||||||||
FNBP3 Antibody - NBP2-38400 from Novus Biologicals
|
||||||||
FNBP3 Antibody - H00055660-B01P from Novus Biologicals
|
||||||||
FNBP3 Antibody - H00055660-B02 from Novus Biologicals
|
||||||||
FNBP3 Polyclonal Antibody - bs-13190R from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13190R-A350 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13190R-A488 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13190R-A555 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13190R-A647 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, Cy3 Conjugated - bs-13190R-Cy3 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, Cy5 Conjugated - bs-13190R-Cy5 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, Cy5.5 Conjugated - bs-13190R-Cy5.5 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, Cy7 Conjugated - bs-13190R-Cy7 from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, FITC Conjugated - bs-13190R-FITC from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, Biotin Conjugated - bs-13190R-Biotin from Bioss
|
||||||||
FNBP3 Polyclonal Antibody, HRP Conjugated - bs-13190R-HRP from Bioss
|
||||||||
Anti-PRPF40A antibody produced in mouse - SAB1400623 from Sigma-Aldrich
|
||||||||
PRPF40A antibody - C-terminal region (ARP62275_P050) - ARP62275_P050 from Aviva Systems Biology
|
||||||||
FNBP3 antibody [C3], C-term - GTX108057 from GeneTex
|
||||||||
PRPF40A antibody - 70R-19549 from Fitzgerald
|