Gene Symbol |
SPZ1
|
Entrez Gene |
84654
|
Alt Symbol |
NYD-TSP1, PPP1R148
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
spermatogenic leucine zipper 1
|
Other Description |
protein phosphatase 1, regulatory subunit 148|spermatogenic leucine zipper protein 1|spermatogenic zip 1|testis-specific protein 1
|
Swissprots |
B2RA21 Q8N4P1 Q8N7E9 Q9BXG8
|
Accessions |
EAW95847 EAW95848 Q9BXG8 AF333098 AAK17995 AI138399 AK098575 BAC05340 AK314007 BAG36718 BC033798 AAH33798 BG723698 BU853967 DQ892123 ABM83049 DQ895317 ABM86243 NM_032567 NP_115956
|
Function |
Transcription factor that binds to the DNA sequence 5'- CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
Tissue Specificity |
Specifically and strongly expressed in the testis. Expressed in several tumor cell lines. {ECO:0000269|PubMed:12778315, ECO:0000269|PubMed:15899793}.
|