Gene Symbol | SPZ1 |
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Entrez Gene | 84654 |
Alt Symbol | NYD-TSP1, PPP1R148 |
Species | Human |
Gene Type | protein-coding |
Description | spermatogenic leucine zipper 1 |
Other Description | protein phosphatase 1, regulatory subunit 148|spermatogenic leucine zipper protein 1|spermatogenic zip 1|testis-specific protein 1 |
Swissprots | B2RA21 Q8N4P1 Q8N7E9 Q9BXG8 |
Accessions | EAW95847 EAW95848 Q9BXG8 AF333098 AAK17995 AI138399 AK098575 BAC05340 AK314007 BAG36718 BC033798 AAH33798 BG723698 BU853967 DQ892123 ABM83049 DQ895317 ABM86243 NM_032567 NP_115956 |
Function | Transcription factor that binds to the DNA sequence 5'- CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Specifically and strongly expressed in the testis. Expressed in several tumor cell lines. {ECO:0000269|PubMed:12778315, ECO:0000269|PubMed:15899793}. |
SPZ1 CRISPR/Cas9 KO Plasmid (h) - sc-417686 from Santa Cruz Biotechnology
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SPZ1 HDR Plasmid (h) - sc-417686-HDR from Santa Cruz Biotechnology
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SPZ1 Double Nickase Plasmid (h) - sc-417686-NIC from Santa Cruz Biotechnology
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SPZ1 Double Nickase Plasmid (h2) - sc-417686-NIC-2 from Santa Cruz Biotechnology
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SPZ1 CRISPR Activation Plasmid (h) - sc-417686-ACT from Santa Cruz Biotechnology
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SPZ1 CRISPR Activation Plasmid (h2) - sc-417686-ACT-2 from Santa Cruz Biotechnology
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SPZ1 Lentiviral Activation Particles (h) - sc-417686-LAC from Santa Cruz Biotechnology
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SPZ1 Lentiviral Activation Particles (h2) - sc-417686-LAC-2 from Santa Cruz Biotechnology
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SPZ1 siRNA (h) - sc-91878 from Santa Cruz Biotechnology
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SPZ1 shRNA Plasmid (h) - sc-91878-SH from Santa Cruz Biotechnology
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SPZ1 shRNA (h) Lentiviral Particles - sc-91878-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU030801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20549 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20549 from Sigma-Aldrich
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SPZ1 siRNA (Human) - CRJ3559 from Cohesion Biosciences
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SPZ1 - MBS8201708 from MyBioSource
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shRNA set against Human SPZ1 (NM_032567.3) - SHH417576 from Creative biogene
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SPZ1 shRNA Plasmid (Human) - CHJ3559 from Cohesion Biosciences
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SPZ1 miRNA 3'UTR clone - MiUTR4H-TG08515 from Creative biogene
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