AMHR2

Gene Symbol AMHR2
Entrez Gene 269
Alt Symbol AMHR, MISR2, MISRII, MRII
Species Human
Gene Type protein-coding
Description anti-Mullerian hormone receptor, type II
Other Description AMH type II receptor|MIS type II receptor|Muellerian inhibiting substance type II receptor|Mullerian inhibiting substance type II receptor|anti-Muellerian hormone type II receptor|anti-Muellerian hormone type-2 receptor
Swissprots Q647K2 B9EGB7 F8W1D2 E9PGD2 A0AVE1 Q16671 Q13762
Accessions AAC50328 AAC78844 CAA61418 CAA62593 EAW96701 Q16671 AF172932 AAD48497 AJ572328 AK313593 AY714878 AAU21221 BC126316 AAI26317 BC136356 AAI36357 CR627318 DB020573 HQ258327 ADR83081 XM_011538173 XP_011536475 XM_011538174 XP_011536476 XM_011538175 XP_011536477 XM_011538176 XP_011536478 XM_011538177 XP_011536479 XM_011538178 XP_011536480 XM_011538179 XP_011536481 XM_011538180 XP_011536482 XM_011538181 XP_011536483 XM_011538182 XP_011536484 XM_011538183 XP_011536485 XM_011538184 XP_011536486 XM_011538185 XP_011536487 XM_011538186 XP_011536488 XM_011538187 XP_011536489 NM_001164690 NP_001158162 NM_001164691 NP_001158163 NM_020547 NP_065434
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

MIS-R2 Antibody - 4518 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from COS cells, mock transfected or transfected with human myc-tagged MIS-R2, using MIS-R2 Antibody (construct kindly provided by Drs. David MacLaughlin and Patricia Donahoe, Massachusetts General Hospital).

MISR II (H-150) - sc-67287 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MISR II (H-150): sc-67287. Western blot analysis of MISR II expression in rat testis (A) and rat ovary (B) tissue extracts.

MISR II (D-9) - sc-377413 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MISR II (D-9): sc-377413. Western blot analysis of MISR II expression in non-transfected: sc-117752 (A) and human MISR II transfected: sc-372823 (B) 293T whole cell lysates.

MISR II (C-15) - sc-66545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MISR II (P-15) - sc-66547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MISR II (N-15) - sc-66546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MISR II (N-15): sc-66546. Western blot analysis of MISR II expression in CCRF-CEM (A), HEK293 (B), HeLa (C), Jurkat (D) and K-562 (E) whole cell lysates.

Anti-AMHR2 antibody - ab197148 from Abcam

Prices $376.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AMHR2 antibody (ab197148) at 1/1000 dilutionLane 1 : HEK293 cell lysateLane 2 : 293T cell lysateLane 3 : MCF7 cell lysate

Anti-AMHR2 antibody - ab118694 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AMHR2 antibody (ab118694) at 1 µg/ml + Mouse brain lysate at 10 µg

Anti-AMHR2 antibody [EPR12225] - ab174311 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12225
All lanes : Anti-AMHR2 antibody [EPR12225] (ab174311) at 1/1000 dilutionLane 1 : NIH:OVCAR-3 cell lysateLane 2 : SK-OV-3 cell lysateLane 3 : Human placenta lysateLysates/proteins at 10 µg per lane.

Anti-AMHR2 antibody [MIG7] - ab64762 from Abcam

Prices $379.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone MIG7
Overlay histogram showing K562 cells stained with ab64762 (red line). The cells were fixed with 80% methanol (5 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab64762, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-AMHR2 antibody - Aminoterminal end - ab75845 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab75845 stained A549 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab75845 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-AMHR2 antibody - C-terminal - ab135636 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AMHR2 antibody - C-terminal (ab135636) at 1/50 dilution + CEM cell line lysate at 35 µg

Anti-AMHR2 / MISRII Antibody (Extracellular Domain, Biotin) - LS-C125959 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50, AP) - LS-C279602 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50, Biotin) - LS-C279605 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50, APC) - LS-C279604 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50, FITC) - LS-C279606 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50) - LS-C327919 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50, Azide-free, HRP) - LS-C279607 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa20-50, PE) - LS-C279608 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AMHR2 / MISRII Antibody (aa13-42) - LS-C98097 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of AMHR2 Antibody in mouse testis tissue lysates (35 ug/lane). AMHR2 (arrow) was detected using the purified antibody.

Anti-AMHR2 / MISRII Antibody (N-Terminus) - LS-C345762 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of AMHR2 Antibody with human 721_B Whole Cell lysate.

Anti-AMHR2 / MISRII Antibody (aa18-144) - LS-C346435 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal
MIS RII in Human Ovary. MIS RII was detected in immersion fixed paraffin-embedded sections of human ovary using Sheep Anti-Human MIS RII Antigen Affinity-purified Polyclonal Antibody at 10 ug/mL overnight at 4°C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown) and counter­stained with hematoxylin (blue).

Anti-AMHR2 / MISRII Antibody - LS-C334775 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using AMHR2 antibody.

Anti-AMHR2 / MISRII Antibody (aa65-91) - LS-C98098 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of AMHR2(arrow) using rabbit polyclonal AMHR2 Antibody (N-term R80). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AMHR2 gene (Lane 2) (Origene Technologies).
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