Gene Symbol | AMHR2 |
---|---|
Entrez Gene | 269 |
Alt Symbol | AMHR, MISR2, MISRII, MRII |
Species | Human |
Gene Type | protein-coding |
Description | anti-Mullerian hormone receptor, type II |
Other Description | AMH type II receptor|MIS type II receptor|Muellerian inhibiting substance type II receptor|Mullerian inhibiting substance type II receptor|anti-Muellerian hormone type II receptor|anti-Muellerian hormone type-2 receptor |
Swissprots | Q647K2 B9EGB7 F8W1D2 E9PGD2 A0AVE1 Q16671 Q13762 |
Accessions | AAC50328 AAC78844 CAA61418 CAA62593 EAW96701 Q16671 AF172932 AAD48497 AJ572328 AK313593 AY714878 AAU21221 BC126316 AAI26317 BC136356 AAI36357 CR627318 DB020573 HQ258327 ADR83081 XM_011538173 XP_011536475 XM_011538174 XP_011536476 XM_011538175 XP_011536477 XM_011538176 XP_011536478 XM_011538177 XP_011536479 XM_011538178 XP_011536480 XM_011538179 XP_011536481 XM_011538180 XP_011536482 XM_011538181 XP_011536483 XM_011538182 XP_011536484 XM_011538183 XP_011536485 XM_011538184 XP_011536486 XM_011538185 XP_011536487 XM_011538186 XP_011536488 XM_011538187 XP_011536489 NM_001164690 NP_001158162 NM_001164691 NP_001158163 NM_020547 NP_065434 |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |