Gene Symbol |
AMHR2
|
Entrez Gene |
269
|
Alt Symbol |
AMHR, MISR2, MISRII, MRII
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
anti-Mullerian hormone receptor, type II
|
Other Description |
AMH type II receptor|MIS type II receptor|Muellerian inhibiting substance type II receptor|Mullerian inhibiting substance type II receptor|anti-Muellerian hormone type II receptor|anti-Muellerian hormone type-2 receptor
|
Swissprots |
Q647K2 B9EGB7 F8W1D2 E9PGD2 A0AVE1 Q16671 Q13762
|
Accessions |
AAC50328 AAC78844 CAA61418 CAA62593 EAW96701 Q16671 AF172932 AAD48497 AJ572328 AK313593 AY714878 AAU21221 BC126316 AAI26317 BC136356 AAI36357 CR627318 DB020573 HQ258327 ADR83081 XM_011538173 XP_011536475 XM_011538174 XP_011536476 XM_011538175 XP_011536477 XM_011538176 XP_011536478 XM_011538177 XP_011536479 XM_011538178 XP_011536480 XM_011538179 XP_011536481 XM_011538180 XP_011536482 XM_011538181 XP_011536483 XM_011538182 XP_011536484 XM_011538183 XP_011536485 XM_011538184 XP_011536486 XM_011538185 XP_011536487 XM_011538186 XP_011536488 XM_011538187 XP_011536489 NM_001164690 NP_001158162 NM_001164691 NP_001158163 NM_020547 NP_065434
|
Function |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Top Pathways |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
|