KRT14

Gene Symbol KRT14
Entrez Gene 3861
Alt Symbol CK14, EBS3, EBS4, K14, NFJ
Species Human
Gene Type protein-coding
Description keratin 14, type I
Other Description CK-14|cytokeratin 14|cytokeratin-14|keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)|keratin, type I cytoskeletal 14|keratin-14
Swissprots Q14715 Q9BUE3 P02533 Q9UBN2 Q9UBN3 Q9UCY4 Q53XY3
Accessions AAB59562 AAF04034 AAF04035 AAF04036 AAF04037 AAF04038 AAF04039 EAW60745 EAW60746 EAW60747 EAW60748 P02533 AK309280 BC002690 AAH02690 BC019097 AAH19097 BC042437 AAH42437 BC094830 AAH94830 BT007186 AAP35850 DB018715 DQ890733 ABM81659 DQ892997 ABM83923 DQ893905 ABM84831 M28646 AAA96689 NM_000526 NP_000517
Function The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. {ECO:0000269|PubMed:11724817}.
Subcellular Location Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern.
Tissue Specificity Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. {ECO:0000269|PubMed:9457912}.

Cytokeratin 14 CRISPR/Cas9 KO Plasmid (h) - sc-400362 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 HDR Plasmid (h) - sc-400362-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 Double Nickase Plasmid (h) - sc-400362-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 Double Nickase Plasmid (h2) - sc-400362-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 CRISPR Activation Plasmid (h) - sc-400362-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 CRISPR Activation Plasmid (h2) - sc-400362-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 Lentiviral Activation Particles (h) - sc-400362-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 Lentiviral Activation Particles (h2) - sc-400362-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cytokeratin 14 siRNA (h) - sc-43309 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytokeratin 14 shRNA Plasmid (h) - sc-43309-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytokeratin 14 shRNA (h) Lentiviral Particles - sc-43309-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU104641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11359 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11359 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KRT14 siRNA (Human) - CRH2621 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KRT14 (NM_000526.4) - SHH327239 from Creative biogene

Category siRNA
Species Reactivities Human

KRT14 shRNA Plasmid (Human) - CHH2621 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KRT14 miRNA 3'UTR clone - MiUTR3H-01266 from Creative biogene

Species Reactivities Human
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