| Gene Symbol |
GHSR
|
| Entrez Gene |
2693
|
| Alt Symbol |
GHDP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
growth hormone secretagogue receptor
|
| Other Description |
GH-releasing peptide receptor|GHRP|GHS-R|ghrelin receptor|growth hormone secretagogue receptor type 1
|
| Swissprots |
Q14D12 Q92847 Q96RJ7 Q92848 Q6ISR8
|
| Accessions |
AAC97506 AAK71539 AAK71540 AAP84357 ABN09829 CAJ34548 CAS01830 CCD32722 EAW78468 EAW78469 Q92847 AY429112 AAR07907 BC069068 AAH69068 BC069374 AAH69374 BC113547 AAI13548 HQ258211 ADR82965 U60179 AAC50653 U60181 AAC50654 NM_004122 NP_004113 NM_198407 NP_940799
|
| Function |
Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). {ECO:0000269|PubMed:10604470, ECO:0000269|PubMed:11322507}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Pituitary and hypothalamus.
|
| Top Pathways |
cAMP signaling pathway, Neuroactive ligand-receptor interaction
|