| Gene Symbol |
PFN4
|
| Entrez Gene |
375189
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
profilin family, member 4
|
| Other Description |
profilin IV|profilin-4
|
| Swissprots |
Q53TL9 Q8NHR9
|
| Accessions |
AAY14666 EAX00760 EAX00761 Q8NHR9 AK292601 BAF85290 BC029523 AAH29523 BC043236 XM_005264292 XP_005264349 XM_006712007 XP_006712070 XM_011532823 XP_011531125 XM_011532824 XP_011531126 NM_199346 NP_955378
|
| Function |
Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin (PubMed:19419568), contrary to other family members. {ECO:0000269|PubMed:19419568}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Tissue Specificity |
Detected in testis (at protein level). {ECO:0000269|PubMed:15591451}.
|
| Top Pathways |
Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton
|